A Baker–Venkataraman retro-Claisen cascade delivers a novel alkyl migration process for the synthesis of amides

Autor:	Timothy J. Snape, Dana Ameen
Rok vydání:	2015
Předmět:	chemistry.chemical_classification chemistry.chemical_compound chemistry Cascade Stereochemistry Amide F100 Organic Chemistry Drug Discovery Substrate (chemistry) Biochemistry Alkyl
Zdroj:	Tetrahedron Letters. 56:1816-1819
ISSN:	0040-4039
Popis:	A simple extension of the carbamoyl Baker–Venkataraman rearrangement has been developed. If residual water in the reaction is not strictly excluded a Baker–Venkataraman retro-Claisen cascade takes place, giving amide products, in which an alkyl group apparently migrates between two functionalities of the substrate.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba898eca666c6924fc0eee848216b981 https://doi.org/10.1016/j.tetlet.2015.02.077 Zobrazit plný text záznamu Full Text from ScienceDirect