Alzheimer’s Disease and Herbal Combination Therapy: A Comprehensive Review
| Autor: | Chandan Shivamallu, Sushma Pradeep, Chandan Dharmashekara, Asad Syed, Shiva Prasad Kollur, Anisha S. Jain, Shashanka K. Prasad |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Combination therapy Disease Review 03 medical and health sciences 0302 clinical medicine Medicine Dementia psychiatrist tangles Treatment regimen business.industry General Neuroscience neuropathologist Neuropathologist Cognition medicine.disease plaques Psychiatry and Mental health Clinical Psychology 030104 developmental biology Geriatrics and Gerontology business Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Journal of Alzheimer's Disease Reports |
| ISSN: | 2542-4823 |
| Popis: | Alzheimer’s disease (AD) was first described in 1907 and got its name after Alois Alzheimer, a German psychiatrist and neuropathologist. This disease starts slow, increasing gradually to worsen in the due course of time. AD is mainly characterized by the associated dementia, which is a decline of cognitive effects such as memory, praxis, and orientation. The dementia is further highlighted by the presence of psychological and behavioral symptoms. Additionally, AD is also associated with the multiple interconnected pathways linked neuropathological changes such as the formation of neurofibrillary tangles and amyloid-β plaques inside the brain. AD therapeutics have been of prime concern over the decades, resulting in the elucidation of promising therapeutic targets. The requirement of AD stage dependent optimized conditions has necessitated a combinatorial approach toward treatment. The priority in AD research has remained to develop disease-modifying and development-reducing drugs for treatment regimens followed during the early and later stages, respectively. |
| Databáze: | OpenAIRE |
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