Frecuencia de tromboembolismo venoso en pacientes hospitalizados con cáncer. Factores de riesgo y eficacia de la tromboprofilaxis farmacológica
Autor: | Gastón Figueroa M, Guillermo Conte L |
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Jazyk: | Spanish; Castilian |
Rok vydání: | 2008 |
Předmět: |
Gastrointestinal bleeding
Chemotherapy medicine.medical_specialty medicine.drug_class business.industry medicine.medical_treatment Low molecular weight heparin General Medicine Odds ratio medicine.disease Gastroenterology Surgery Breast cancer Internal medicine Neoplasms medicine Vomiting Fibrinolytic agents cardiovascular diseases medicine.symptom business Lung cancer Fibrinolytic agent Venous thromboembolism |
Zdroj: | Revista médica de Chile v.136 n.12 2008 SciELO Chile CONICYT Chile instacron:CONICYT |
Popis: | Background: Hospitalized patients with cancer have a high risk of venous thromboembolism (VTE). Aim: To study the frequency of VTE and its risk factors in hospitalized patients with cancer. Material and methods: Retrospective analysis of clinical records of patients with cancer, hospitalized at a university hospital between 2002 and 2004. Patients with the diagnosis of VTE at admission or using anticoagulants, were excluded from the analysis. Results: The medical records of 366 patients were reviewed. Fifty three percent had a digestive cáncer, 19% lung cáncer, 10% breast cancer and 18% had a tumor of other origin. In 77%, the tumor was in an advanced stage. The most common admission diagnoses were pneumonía, vomiting and dehydration, gastrointestinal bleeding and urinary infection. In 125 patients (34%) pharmacological thrombo-prophylaxis was not used and 242 (66%) received regular or low molecular weight heparin. VTE was detected in 11 patients (3%) and was significantly more common among patients not receiving thrombo prophylaxis compared to those receiving heparin (6.4% and 1.2%, respectively p =0.014). Factors associated to VTE were a history ofprevious VTE with an odds ratio (OR) of 12.9 (p |
Databáze: | OpenAIRE |
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