Dermatitis herpetiformis in Japan: An Update
| Autor: | Mina Shimizu, Hiroko Nanko, Hiroshi Shimizu, Masao Matsumoto, Mariko Shibahara, Masahide Kubo, Shuko Nonaka, Michiko Ikeda, Naoko Kanda |
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| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
Dermatitis Herpetiformis Common disease Dermatology Mongoloid Risk Assessment Severity of Illness Index Coeliac disease Japan Risk Factors Gluten-sensitive enteropathy Dermatitis herpetiformis Humans Medicine business.industry Incidence Incidence (epidemiology) Biopsy Needle Middle Aged Prognosis medicine.disease Fluorescent Antibody Technique Direct Female business Dapsone |
| Zdroj: | Dermatology. 204:37-42 |
| ISSN: | 1421-9832 1018-8665 |
| DOI: | 10.1159/000051808 |
| Popis: | Background: Although dermatitis herpetiformis (DH) is a relatively common disease in Caucasian populations, it is rare in Asian populations including the Japanese. We encountered a Japanese case of DH which showed granular IgA and C3 deposits in the papillary dermis and which was associated with gluten-sensitive enteropathy but no HLA-B8/DR3/DQ2. Objective: The purpose of this study is to describe the characteristics of Japanese DH cases, since most of them have been reported in Japanese language and dermatologists outside Japan are not familiar with the characteristics of Japanese DH. Methods: We have reviewed all 34 Japanese DH cases reported previously. Results: We found several features of Japanese DH compared with Caucasian DH, such as a high frequency of the fibrillar pattern, rarity of gluten-sensitive enteropathy and an absence of the HLA-B8/DR3/DQ2 haplotype. Conclusion: There might be significant differences in pathophysiology between Caucasian and Japanese DH cases. |
| Databáze: | OpenAIRE |
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