The relationship between gastric cancer, its precancerous lesions and bile reflux: A retrospective study

Autor: Yong Quan Shi, Qi He, Jie Wang, Chen Chen Feng, Jian Zhang, Jing Zhao, Ying Qi, Dan Li, Dong Lin Zhang, Ya Ping Cao, Si Ran Wu, Wen Zhu Yao, Na Wang, Huan Huan Lv
Rok vydání: 2020
Předmět:
Adult
Male
medicine.medical_specialty
Adolescent
Chronic gastritis
intestinal metaplasia
Gastroenterology
Bile reflux
Young Adult
03 medical and health sciences
0302 clinical medicine
Risk Factors
Stomach Neoplasms
Internal medicine
Gastroscopy
gastric neoplasms
medicine
Humans
Aged
Retrospective Studies
medicine.diagnostic_test
business.industry
Bile Reflux
Stomach
digestive
oral
and skin physiology
gastritis
Intestinal metaplasia
Cancer
Retrospective cohort study
Middle Aged
medicine.disease
digestive system diseases
Endoscopy
Gastrointestinal Tract
Gastric Mucosa
030220 oncology & carcinogenesis
Disease Progression
Female
Original Article
030211 gastroenterology & hepatology
ORIGINAL ARTICLES
Gastritis
medicine.symptom
business
Precancerous Conditions
precancerous lesions
Gastric Neoplasm
Zdroj: Journal of Digestive Diseases
ISSN: 1751-2980
1751-2972
DOI: 10.1111/1751-2980.12858
Popis: Objective To evaluate the relationship between gastric cancer (GC) and precancerous lesions and bile reflux. Methods Medical records of 30 465 participants who underwent gastroscopy between January and December 2018 in our center were reviewed. Their age, sex, time of endoscopy, endoscopic/histologic diagnosis and grade of bile reflux were recorded. The participants were further divided into the chronic gastritis group (n = 27 807), a precancerous lesion group (n = 1943) and a GC group (n = 715). The χ2 tests and hierarchical analyses were performed. Results Patients aged 18‐27 years had a higher bile reflux rate than those aged 28‐37 and 68‐75 years (P 0.05), but differed between morning and afternoon when they underwent the endoscopy (P = 0.000). There was an interrelationship between the severity of gastric mucosal disease and bile reflux grade (r = 0.171). After excluding the effects of sex, age and time of endoscopy on bile reflux, bile reflux rate in chronic gastritis and precancerous lesions was lower than in gastric cancer (P
Databáze: OpenAIRE
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