Reduction of Bladder Volume after BCG Immunotherapy

Autor: Zhengtong Lv, Changzhao Yang, Yuan Li
Rok vydání: 2020
Předmět:
Zdroj: Urologia Internationalis. 105:155-158
ISSN: 1423-0399
0042-1138
DOI: 10.1159/000510167
Popis: Bacillus Calmette-Guérin (BCG) immunotherapy is the most effective treatment for carcinoma in situ and high-risk non-muscle invasive bladder cancer (NMIBC). However, it can also provoke diverse side effects. We found 1 patient with a significantly and rapidly reduced bladder volume after the instillation of BCG. Few such cases and corresponding treatments have been reported. We speculated that the tuberculosis infection existed, so antitubercular therapy was given. After a 3-month oral intake of rifampicin, isoniazid, and ofloxacin, the volume of bladder returned to normal and the voiding symptoms disappeared. This case indicated that the reduction of bladder volume caused by BCG instillation could be treated with antitubercular therapy. Prompt and accurate diagnosis was important for the management.
Databáze: OpenAIRE