Intestinal occlusion by stenotic neuroendocrine tumours of left colon and concomitant association with small bowel gastrointestinal stromal tumours: A case report
| Autor: | Antonio Margari, Arcangelo Picciariello, V.L. Pinto, M. Amoruso, V. Papagni, Dario D'Abbicco |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Adenocarcinoma Asymptomatic Gastroenterology Article Metastasis Lesion 03 medical and health sciences 0302 clinical medicine Internal medicine medicine neoplasms Colorectal GiST business.industry medicine.disease Gastrointestinal stromal tumours digestive system diseases NET 030220 oncology & carcinogenesis Concomitant Intestinal occlusion 030211 gastroenterology & hepatology Surgery medicine.symptom business GIST |
| Zdroj: | International Journal of Surgery Case Reports |
| ISSN: | 2210-2612 |
| Popis: | Highlights • Gastrointestinal stromal tumours (GIST) and Neuroendocrine tumours (NET) of the gastroenteropancreatic tract are rare neoplasms. • Treatment for colonic NETs was similar to colonic adenocarcinoma, with segmental resection and lymphadenectomy. • The associationof GIST and NET is difficult to suspect Serum CgA remains the most important biochemical marker in the diagnostics, monitoring, and establishing the prognosis in colorectal NETs. • Early diagnosis of concomitant tumors such as GIST and NET will guarantee a better outcome of patients. Introduction The association between Gastrointestinal Stromal Tumours (GIST) and Neuroendocrine Tumours (NET) is very rare. These tumours have various clinical expressions and sometimes are asymptomatic. Synchronous NETs and GISTs have been already described in literature in few case reports. On the other hand, there is no mention of concomitant presence of discending colon NEC-G3 and small intestinal GIST. Presentation of case: we presented a case of a patient with clinical evidence of intestinal occlusion and radiological and intraoperative aspects of an adenocarcinoma of the left colon with a single metastasis on small bowel. The pathology analysis of the tumour showed a stenotic left colon NEC-G3 and a small bowel GIST. Discussion In this case report GIST was surgically treated as a small bowel ripetitive lesion and NET as a left colon adenocarcinoma. These tumours may have a similar presentation in terms of symptoms, endoscopic findings and imaging results. Conclusion Concomitant NEC and GIST is rare but it is important to investigate patients before surgery in order to distinguish these from other tumours because of the different prognosis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|