Epidemiological and bacteriological profiles in children with burns
| Autor: | Sonia Ben Khalifa, Mayssa Daiki, Amjed Fekih Hassen |
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| Rok vydání: | 2014 |
| Předmět: |
Male
Staphylococcus aureus medicine.medical_specialty Poison control Critical Care and Intensive Care Medicine Cohort Studies Interquartile range Sepsis Internal medicine Drug Resistance Bacterial Enterobacter cloacae Case fatality rate Humans Medicine Pseudomonas Infections Prospective Studies Child Oxacillin Cause of death Piperacillin Cross Infection business.industry Septic shock Mortality rate Enterobacteriaceae Infections General Medicine Staphylococcal Infections medicine.disease Anti-Bacterial Agents Surgery Child Preschool Pseudomonas aeruginosa Wound Infection Emergency Medicine Female Gentamicins Burns business Total body surface area medicine.drug |
| Zdroj: | Burns. 40:1040-1045 |
| ISSN: | 0305-4179 |
| DOI: | 10.1016/j.burns.2013.10.020 |
| Popis: | Objectives The aim of our study is to determine the most prevalent bacteria responsible for nosocomial infection (NI) in burned children. Materials and methods A prospective analytic study was conducted over a period of 30 months at the Children's Hospital of Tunisia. All burned children were enrolled. Results A total of 185 children were hospitalised during the study period. The mean age was 30 months (interquartile range, IR:18; 48). The gender ratio of the study population was 1.3 (104 males and 81 females). The mean total body surface area burned (TBSA) was 10% (IR:6; 16). The incidence rate of NI was 39.1 NIs per 1000 patient-days and two-thirds of the infections were polymicrobial. The most common isolated micro-organisms were methicillin-susceptible Staphylococcus aureus (MSSA, 57.7%), wild-type Pseudomonas aeruginosa (35.9%) and wild-type Enterobacter cloacae (26.9%). The case fatality rate was 5.9% corresponding to a crude death rate of 1.32 deaths per year. Septic shock with multiple organ failure was the leading cause of death. Conclusion The most common micro-organisms responsible for NI in our series were of the wild-type phenotype. Thus, on suspicion of sepsis, empiric antibiotic treatment combining piperacillin, oxacillin and gentamicin can be proposed until identification of the causative microorganism is available. |
| Databáze: | OpenAIRE |
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