An electrochemical paper-based analytical sensor for one-step latex protein detection

Autor:	Jaruwan Mettakoonpitak, Preeyanuch Junkong, Aphiwan Saenonphut, Tanagorn Kwamman, Atitaya Siripinyanond, Charles S. Henry
Rok vydání:	2022
Předmět:	Latex Electrochemistry Environmental Chemistry Graphite Electrochemical Techniques Allergens Electrodes Biochemistry Carbon Spectroscopy Analytical Chemistry
Zdroj:	The Analyst. 147:932-939
ISSN:	1364-5528 0003-2654
DOI:	10.1039/d1an02067f
Popis:	Exposure to natural rubber latex (NRL) can result in sensitivity to NRL protein with resulting allergic reactions. Low-cost, portable, simple, sensitive analytical tools for NRL protein measurements are needed for rapid and accurate assessments of allergenic risks at the point-of-care (POC) instead of using traditional methods that require large and expensive instruments, long-time analysis, and complex sample preparation steps. Here, an electrochemical paper-based analytical device (ePAD) is presented by combining sample preparation and electrochemical detection within a single device to offer a one-step NRL analysis. The lack of antibodies and/or enzymes against NRL makes POC analysis difficult. In this work, detection is based on electrochemical measurement of the remaining Cu after
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba60a097a7d8b9da4b14bd925356cd12 https://doi.org/10.1039/d1an02067f Zobrazit plný text záznamu