Position of Igl-1, md, and Bst loci on chromosome 16 of the mouse
| Autor: | M T Davisson, Melvin Cohn, Ruth Epstein, E C Akeson, K Lehmann |
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| Rok vydání: | 1986 |
| Předmět: |
Male
Genetic Linkage Immunology Locus (genetics) Biology Immunoglobulin light chain law.invention Centimorgan Mice Chromosome 16 Immunoglobulin lambda-Chains law Genetics Animals Hair Color Gene Crosses Genetic Chromosome Mapping Pigments Biological Molecular biology Mice Inbred C57BL Backcrossing AKR murine leukemia virus Recombinant DNA biology.protein Female Immunoglobulin Light Chains Antibody |
| Zdroj: | Immunogenetics. 23(2) |
| ISSN: | 0093-7711 |
| Popis: | The experiments described here delineate the position of the chromosome 16 markers Igl-1 (immunoglobulin lambda 1, light chain), md (mahoganoid), and Bst (belly spot and tail), and suggest their location relative to the endogenous proviral locus Akv-2, which is linked within 5.9 centimorgans to Igl-1 (Epstein et al. 1984). The data from an intercross and a three-point backcross detailed herein show the order of these three genes and distances between them to be: centromere-md-10.4 +/- 1.6-Igl-1-15.6 +/- 2.6-Bst. Using a recombinant chromosome recovered in the intercross, we have constructed a stock homozygous for md and Igl-1b (KpnI-), that will aid in mapping other genes on chromosome 16. |
| Databáze: | OpenAIRE |
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