Identification of the Xenopus laevis cDNA for EXT1: A Phylogenetic Perspective
| Autor: | Dan E. Wells, Nicholas Brown, April Hill, M.S. Hill |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
musculoskeletal diseases
DNA Complementary Molecular Sequence Data Xenopus Biology N-Acetylglucosaminyltransferases Biochemistry Xenopus laevis chemistry.chemical_compound Endocrinology Sequence Analysis Protein Complementary DNA Genetics Animals Humans Gene family Amino Acid Sequence Molecular Biology Gene Phylogeny Heparan Sulfate Biosynthesis Phylogenetic tree Heparan sulfate biology.organism_classification Gastrulation chemistry Sequence Alignment human activities |
| Zdroj: | DNA Sequence. 13:85-92 |
| ISSN: | 1042-5179 |
| Popis: | The EXT family of genes is involved in the developmentally important biosynthesis of heparan sulfate molecules. Members of the EXT family have a demonstrated role in gastrulation, wing formation in flies, and proper bone development in vertebrates. EXT family members have been isolated from several phylogenetically diverse species. We report here, the isolation of the first Xenopus laevis EXT1 family member and discuss the evolutionary origins of this gene family. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|