Anorectal malformation & Hirschsprung’s disease: A cross-sectional comparison of quality of life and bowel function to healthy controls
| Autor: | Seyed Ehsan Saffari, Yee Low, Te-Lu Yap, Shireen Anne Nah, Caroline C P Ong, Anette Sundfor Jacobsen, Lin Yin Ong |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Parents Pediatrics medicine.medical_specialty Adolescent Disease Young Adult 03 medical and health sciences 0302 clinical medicine Quality of life Surveys and Questionnaires 030225 pediatrics Statistical significance Humans Medicine Hirschsprung Disease Prospective Studies Bowel function Child Prospective cohort study Hirschsprung's disease Core (anatomy) business.industry General Medicine Evidence-based medicine medicine.disease Anorectal Malformations Cross-Sectional Studies Child Preschool Pediatrics Perinatology and Child Health Quality of Life Female 030211 gastroenterology & hepatology Surgery Self Report business |
| Zdroj: | Journal of Pediatric Surgery. 53:1550-1554 |
| ISSN: | 0022-3468 |
| Popis: | Patients with anorectal malformation (ARM) and Hirschsprung's disease (HD) face long-term disturbance in bowel function even after definitive surgery. This study evaluates the quality of life (QOL) of patients with ARM and HD, and compares them to healthy controls using self-report questionnaires.A prospective study was performed recruiting patients with ARM or HD from September 2013 to December 2014 who had primary surgery done in our institution at least 2 years prior to participation. Age-matched and gender-matched controls were enrolled from our patients with minor outpatient complaints. All participants completed the following PedsQL™ scales (maximum score 100): 4.0 Generic Core Scales, 3.0 General Well-Being (GWB) Scale and 2.0 Family Impact (FI) Module. All were also scored on bowel function (BFS), with a maximum score 20. Appropriate statistical analysis was performed, with significance level0.05.There were 193 participants: 87 controls, 62 ARM, 44 HD. When comparing Core, GWB and FI scores, there were no significant differences between groups although controls had best scores indicating best QOL and general wellbeing, with least impact of the child's health on the family. BFS was significantly different with controls having best and ARM worst scores. There were no significant differences in scores between parent and child indicating intradyad consistency. There was significant positive correlation between BFS and Core (p0.0001), and between BFS and GWB scores (p0.005); and significant negative correlation between BFS and FI scores (p0.0001).Bowel function impacts quality of life. Those with ARM and HD can achieve good quality of life comparable to controls, based on patient and caregiver self-reported outcomes.Prospective comparative study LEVEL OF EVIDENCE: Level II. |
| Databáze: | OpenAIRE |
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