Gold Nanocage-Based Electrochemical Sensing Platform for Sensitive Detection of Luteolin
| Autor: | Ruyi Zou, Xiaoqin Chen, Wei Sun, Xiaobao Li, Taiming Shao, Yanyan Niu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Materials science
gold nanocages 02 engineering and technology 010402 general chemistry Electrochemistry lcsh:Chemical technology 01 natural sciences Biochemistry Article Analytical Chemistry chemistry.chemical_compound Nanocages lcsh:TP1-1185 Electrical and Electronic Engineering luteolin Instrumentation Detection limit 021001 nanoscience & nanotechnology Atomic and Molecular Physics and Optics 0104 chemical sciences Electrochemical gas sensor carbon ionic liquid electrode Chemical engineering chemistry electrochemistry Electrode Ionic liquid 0210 nano-technology Luteolin Chemically modified electrode |
| Zdroj: | Sensors Volume 18 Issue 7 Sensors, Vol 18, Iss 7, p 2309 (2018) Sensors (Basel, Switzerland) |
| ISSN: | 1424-8220 |
| DOI: | 10.3390/s18072309 |
| Popis: | A simple and sensitive electrochemical sensor was developed for the detection of tracelevels of luteolin. The sensoris based on a novel type of chemically modified electrode: gold nanocage (AuNCs)-modified carbon ionic liquid electrode (CILE). To construct this electrochemical sensing platform for luteolin, CILE is initially prepared by using 1-hexylpyridinium hexafluorophosphate as the binder and then AuNCs are coated on the surface of CILE to fabricate AuNCs-modified CILE (AuNCs/CILE). Electrochemical studies have shown that AuNCs/CILE can exhibit enhanced electrocatalytic activity toward the redox reaction of luteolin, therefore, the redox peak current of luteolin can be greatly improved, resulting in the high sensitivity of the developed sensor. Under the optimal conditions, the oxidation peak currents of the sensor increase linearly with an increase in the luteolin concentration in a range from 1 to 1000 nM with a detection limit of 0.4 nM, which is lower than those of most reported electrochemical luteolin sensors. Moreover, the reproducibility, precision, selectivity, and stability of this sensor are excellent. Finally, the sensing system was applied to the analysis of luteolin-spiked drug samples and the recovery in all cases was 95.0&ndash 96.7%, indicating the potential application of this simple, facile, and sensitive sensing system in pharmaceutical analysis. |
| Databáze: | OpenAIRE |
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