A New Approach to Recognize Neonatal Impaired Kidney Function
| Autor: | Sofia Perazzo, Billie L. Short, Mary Revenis, Patricio E. Ray, An N. Massaro |
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| Rok vydání: | 2020 |
| Předmět: |
Pediatrics
medicine.medical_specialty Neonatal intensive care unit medicine.medical_treatment 030232 urology & nephrology Renal function 030204 cardiovascular system & hematology behavioral disciplines and activities serum creatinine Hypoxic Ischemic Encephalopathy 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Clinical Research medicine Mechanical ventilation Creatinine business.industry Medical record renal function Acute kidney injury Gestational age medicine.disease acute kidney injury chemistry Nephrology neonate business first week of life |
| Zdroj: | Kidney International Reports |
| ISSN: | 2468-0249 |
| DOI: | 10.1016/j.ekir.2020.09.043 |
| Popis: | Introduction Previous studies in term newborns with hypoxic ischemic encephalopathy showed that the rate of serum creatinine (SCr) decline during the first week of life could be used to identify newborns with impaired kidney function (IKF) who are missed by standard definitions of neonatal acute kidney injury (nAKI). Methods Retrospective review of the medical records of 329 critically ill newborns ≥27 weeks of gestational age (GA) admitted to a level 4 neonatal intensive care unit (NICU). We tested the hypothesis that the rate of SCr decline combined with SCr thresholds provides a sensitive approach to identify term and preterm newborns with IKF during the first week of life. Results Excluding neonates with nAKI, an SCr decline Graphical abstract |
| Databáze: | OpenAIRE |
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