Substrate mapping of the left atrium in persistent atrial fibrillation: spatial correlation of localized complex conduction patterns in global charge-density maps to low-voltage areas in 3D contact bipolar voltage maps
| Autor: | Antonio Bisignani, Thiago Guimarães Osório, Juan Sieira, Gian-Battista Chierchia, Joerelle Mojica, Gezim Bala, Gaetano Paparella, Erwin Ströker, Pedro Brugada, Serge Boveda, Carlo de Asmundis, Vincenzo Mitraglia, Ingrid Overeinder, Annelies Vanderper, Maysam Al Houssari, Federico Cecchini |
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| Přispěvatelé: | Cardiology, Clinical sciences, Heartrhythmmanagement, Faculty of Medicine and Pharmacy, Cardio-vascular diseases, Medical Imaging |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Spatial correlation Substrate mapping medicine.medical_treatment 030204 cardiovascular system & hematology Dipole density noncontact mapping Low-voltage areas Article 03 medical and health sciences 0302 clinical medicine Heart Rate Physiology (medical) Internal medicine Atrial Fibrillation medicine Humans Sinus rhythm 030212 general & internal medicine Heart Atria Coronary sinus business.industry Charge density Atrial fibrillation Ablation medicine.disease SuperMap algorithm 3D-mapping Cardiology Catheter Ablation business Cardiology and Cardiovascular Medicine Electrophysiologic Techniques Cardiac Low voltage |
| Zdroj: | Journal of Interventional Cardiac Electrophysiology |
| ISSN: | 1572-8595 1383-875X |
| Popis: | Purpose This study aimed to investigate the spatial relationship between low-voltage areas (LVAs) in bipolar voltage mapping (BVM) and localized complex conduction (LCC)-cores in a global, non-contact, charge-density-based imaging, and mapping system (AcM). Methods Patients with history of index PVI for PsAF and scheduled for a repeat ablation procedure for recurrence of the same arrhythmia were enrolled between August 2018 and February 2020. All patients underwent both substrate mappings of the left atrium (LA) with the CARTO 3D map-ping system and with AcM. Results Ten patients where included in our analysis. All presented with persistency of PVI in all veins at the moment of repeat procedure. There was no linear relationship in BVM maps between SR and CSd (correlation coefficient 0.31 ± 0.15), SR and CSp (0.36 ± 0.12) and CSd and CSp (0.43 ± 0.10). The % overlap of localized irregular activation (LIA), localized rotational activation (LRA) and Focal (F) regions with LVA was lower at 0.2 mV compared to 0.5 mV (4.97 ± 7.39%, 3.27 ± 5.25%, 1.09 ± 1.92% and 12.59 ± 11.81%, 7.8 ± 9.20%, 4.62 ± 5.27%). Sensitivity and specificity are not significantly different when comparing composite maps with different LVA cut-offs. AURC was 0.46, 0.48, and 0.39 for LIA, LRA, and Focal, respectively. Conclusion Due to wave front direction dependency, LVAs mapped with BVM in sinus rhythm and during coronary sinus pacing only partially overlap in patients with PsAF. LCC-cores mapped during PsAF partially co-localize with LVAs. |
| Databáze: | OpenAIRE |
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