Combined Bacterial and Herpes Simplex Virus Keratitis following Small-Incision Lenticule Extraction for the Correction of Myopia
| Autor: | Natalia Quiroz-Casian, Arturo Ramirez-Miranda, Enrique O Graue-Hernandez, Valeria Oliva-Biénzobas, Jesus Cabral-Macias, Simran Mangwani-Mordani, Alejandro Navas |
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| Rok vydání: | 2021 |
| Předmět: |
Keratitis
Ganciclovir medicine.medical_specialty genetic structures business.industry medicine.medical_treatment Case Report RE1-994 Herpes simplex virus Infectious Keratitis medicine.disease_cause medicine.disease eye diseases Ophthalmology Moxifloxacin Prednisolone Medicine Small incision lenticule extraction business Saline Small-incision lenticule extraction medicine.drug |
| Zdroj: | Case Reports in Ophthalmology Case Reports in Ophthalmology, Vol 12, Iss 1, Pp 227-231 (2021) |
| ISSN: | 1663-2699 |
| DOI: | 10.1159/000511374 |
| Popis: | A 28-year-old male presented unilateral visual loss, intense ocular pain, redness and intraocular hypertension in his right eye 2 days after undergoing small-incision lenticule extraction (SMILE) in both eyes. Initial examination of the affected eye revealed the presence of white infiltrates within the corneal interface, as well as a central epithelial defect. The patient was diagnosed with infectious keratitis, posteriorly the eye was irrigated with balanced saline solution and treatment was initiated with hourly moxifloxacin 0.5%. Since this approach failed to resolve symptoms, a sample from the interface was obtained for PCR assay, which revealed the presence of herpes simplex virus DNA, confirming the cause of the infection. The patient was prescribed a regimen of oral acyclovir, topical ganciclovir and prednisolone. Clinical improvement following resolution of the epithelial defect was observed. Although rare, herpetic keratitis following SMILE is best managed via early diagnosis and initiation of appropriate anti-herpetic treatment. |
| Databáze: | OpenAIRE |
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