[3 + 2] Cycloaddition of Oxazol-5-(4H)-ones with Nitrones for Diastereoselective Synthesis of Isoxazolidin-5-ones

Autor:	Juan Du, Xiao-Qin Chen, Hong-Wu Zhao, Yu-Di Zhao, Zhao Yang, Hai-Liang Pang, Ting Tian, Ning-Ning Feng, Yue-Yang Liu, Xiu-Qing Song, Bo Li
Rok vydání:	2016
Předmět:	Structure analysis 010405 organic chemistry Chemistry Chemical structure Organic Chemistry Organic chemistry Nanotechnology Physical and Theoretical Chemistry 010402 general chemistry 01 natural sciences Biochemistry Cycloaddition 0104 chemical sciences
Zdroj:	Organic Letters. 19:26-29
ISSN:	1523-7052 1523-7060
Popis:	In the presence of TMSCl, the [3 + 2] cycloaddition of oxazol-5-(4H)-ones with nitrones proceeded smoothly and furnished the desired isoxazolidin-5-ones with high diastereoselectivities in reasonable chemical yields. The chemical structure of the title compounds was firmly confirmed by X-ray single-crystal structure analysis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba2f913a20375315ea2226ab13101cca https://doi.org/10.1021/acs.orglett.6b03206 Zobrazit plný text záznamu