Alkaloid inspired spirocyclic oxindoles from 1,3-dipolar cycloaddition of pyridinium ylides

Autor:	William Lewis, Jonathan Day, Richard A. Castledine, James Dowden, Maliha Uroos, Ben McKeever-Abbas
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	Indoles Strychnofoline Molecular Structure Chemistry Stereochemistry Alkaloid Organic Chemistry Pyridinium Compounds Stereoisomerism Biochemistry Cycloaddition Oxindoles chemistry.chemical_compound Alkaloids Cyclization Yield (chemistry) 1 3-Dipolar cycloaddition Organic chemistry Oxindole Spiro Compounds Pyridinium Physical and Theoretical Chemistry
ISSN:	1477-0520 1477-0539
Popis:	Cycloaddition reactions between pyridinium ylides and 3-alkenyl oxindoles that proceed in high yield and with very good regio- and diastereoselectivity are reported. The resulting cycloadducts have the same stereochemistry of biologically active oxindole alkaloids, such as strychnofoline.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba19250af40e205e228e858cd5e257d1 https://nottingham-repository.worktribe.com/file/717062/1/Line_102_Alkaloid_inspired_spirocyclic.pdf Zobrazit plný text záznamu