Cadaver donor kidney retransplantation in the pediatric patient: complications and long-term outcome
| Autor: | Carlos Hernández-Fernández, D. Subirá-Ríos, F. Herranz-Amo, G. Bueno-Chomón, Ramón Durán-Merino, Fernando Verdú-Tartajo, Gabriel Ogaya-Pinies, Enrique Lledó-García, M. Moralejo-Gárate, Augusto Luque-de Pablos, J. M. Diez-Cordero, Dolores Morales |
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| Rok vydání: | 2010 |
| Předmět: |
Nephrology
Adult Male medicine.medical_specialty Time Factors Adolescent Urology Urinary system End stage renal disease Young Adult Postoperative Complications Internal medicine medicine Cadaver Humans Child Kidney transplantation Retrospective Studies Kidney business.industry Infant Middle Aged medicine.disease Kidney Transplantation Tissue Donors Surgery Transplantation Survival Rate surgical procedures operative medicine.anatomical_structure Treatment Outcome El Niño Child Preschool Retreatment Female Complication business |
| Zdroj: | The Journal of urology. 185 |
| ISSN: | 1527-3792 |
| Popis: | We compared the outcome of second and third kidney allografts with that of the first kidney allograft in pediatric recipients.We classified 173 cadaveric kidney recipients into 2 groups. Group 1 comprised 120 first transplants and group 2 comprised 53 retransplants, including 43 second and 10 third transplants. We compared demographic characteristics and survival in groups 1 and 2.Group 1 consisted of 78 boys and 42 girls with a mean ± SD age of 11.5 ± 4.2 years. Group 2 consisted of 37 boys and 16 girls with a mean age of 10.4 ± 4.7 years. One, 5, 10 and 15-year graft survival rates were 78.7%, 64.3%, 54.5% and 50.7% for first transplants vs 82.8%, 57.8%, 57.8% and 41.3%, respectively, for retransplants (p = 0.757). Patient survival at 1, 5 and 15-year was 95.8%, 89.6%, 84.9% in the first transplant group vs 93.6%, 93.6% and 93.6%, respectively, in the retransplant group (p = 0.0.63). Graft survival was significantly higher in patients who did vs did not receive calcineurin inhibitors in the 2 groups (p = 0.02).Kidney retransplantation in the pediatric population can yield excellent long-term outcomes, especially in patients treated with calcineurin inhibitors. |
| Databáze: | OpenAIRE |
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