Brain fetal magnetic resonance imaging to evaluate maturation of normal white matter during the third trimester of pregnancy
| Autor: | Jean Delmas, Amandine Crombé, Jean-François Chateil, Camille Letissier, Lydie Chérier |
|---|---|
| Přispěvatelé: | Centre de résonance magnétique des systèmes biologiques (CRMSB), Centre National de la Recherche Scientifique (CNRS)-Université de Bordeaux (UB) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pregnancy Trimester
Third [SDV]Life Sciences [q-bio] Thalamus 030218 nuclear medicine & medical imaging White matter 03 medical and health sciences 0302 clinical medicine Cerebrospinal fluid Pregnancy medicine Humans Effective diffusion coefficient Radiology Nuclear Medicine and imaging Child ComputingMilieux_MISCELLANEOUS Retrospective Studies Neuroradiology medicine.diagnostic_test business.industry Brain Infant Reproducibility of Results Gestational age Magnetic resonance imaging Magnetic Resonance Imaging White Matter Pons Diffusion Magnetic Resonance Imaging medicine.anatomical_structure Pediatrics Perinatology and Child Health Female Nuclear medicine business 030217 neurology & neurosurgery |
| Zdroj: | Pediatric Radiology Pediatric Radiology, Springer Verlag, 2021, 51 (10), pp.1826-1838. ⟨10.1007/s00247-021-05064-1⟩ |
| ISSN: | 0301-0449 1432-1998 |
| DOI: | 10.1007/s00247-021-05064-1⟩ |
| Popis: | Quantitative magnetic resonance imaging (MRI) could improve the estimation of fetal brain maturation and the interpretation of white matter signal intensity in pathological conditions. To investigate T2-based and diffusion-weighted imaging (DWI) measurements for the evaluation of fetal brain maturation during the last trimester of pregnancy. One hundred sixty-eight fetal brain MRIs were retrospectively analyzed (age range: 28–37 weeks of gestation) after ensuring that none of the children developed psychomotor or cognitive impairment (median follow-up: 4.7 years). Bilateral regions of interest were drawn on the frontal, occipital, parietal and temporal lobes from T2-W imaging and DWI, when available, to evaluate signal intensity and apparent diffusion coefficient (ADC) values. Ratios were calculated with two references (pons or thalamus and cerebrospinal fluid) to standardize signal intensities. Reproducibility was evaluated with intraclass correlation coefficients (ICCs) and Bland-Altman plots. Correlations with gestational age were evaluated with univariate and multivariate linear regressions. T2 measurements were achieved in all cases, and DWI was available in 37 cases. Measurements and ratios were reproducible in eight localizations (i.e. intra- and interobserver ICCs >0.5): frontal T2/thalamus, parietal T2/thalamus, occipital T2/pons, parietal ADC/thalamus, occipital ADC/pons, temporal ADC/pons, occipital ADC and temporal ADC. The frontal T2/thalamus and parietal T2/thalamus correlated with gestational age (P |
| Databáze: | OpenAIRE |
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