Sex differences in the anatomy of coronary artery disease
| Autor: | Athanassios Antonopoulos, Gregory P. Vyssoulis, Panaghiotis Petropoulakis, Pavlos Toutouzas, Aristides Androulakis, Michael Kyriakidis, Theodoros Apostolopoulos, John Barbetseas |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Adult
Male Cardiac Catheterization medicine.medical_specialty Epidemiology medicine.medical_treatment Hypercholesterolemia Coronary Disease Coronary Angiography Coronary artery disease Risk Factors Internal medicine Diabetes mellitus Diabetes Mellitus Prevalence medicine Humans Prospective Studies Prospective cohort study Aged Cardiac catheterization Sex Characteristics Greece business.industry Incidence Incidence (epidemiology) Smoking Age Factors Middle Aged medicine.disease Coronary Vessels medicine.anatomical_structure Hypertension Cardiology Female business Artery Sex characteristics |
| Zdroj: | Journal of Clinical Epidemiology. 48:723-730 |
| ISSN: | 0895-4356 |
| DOI: | 10.1016/0895-4356(94)00194-u |
| Popis: | In a prospective study, the extent and severity of coronary artery disease (CAD) as well as the location of coronary stenoses were studied comparatively, in relation to age and sex, in 192 consecutive women vs 543 selected men, who all underwent coronary angiography during the same time period, and who were found to have significant CAD. Overall, the age of women (59 +/- 8 years) was higher than that of men (55 +/- 8 years), p < 0.001. Also, the prevalence of smoking was higher in men (81% vs 31%, p = 0.0000) and that of diabetes mellitus in women (29% vs 12%, p = 4 x 10(-6)). In addition, women over 50 years old had a higher incidence of hypertension (51% vs 32%, p = 6 x 10(-5)). Although in both sexes the prevalence of multivessel CAD increased with age, the prevalence of one-vessel CAD was significantly more and that of three-vessel CAD significantly less common in women than in men, both overall (35% vs 16%, p = 4 x 10(-8) and 36% vs 54%, p = 2 x 10(-5), respectively) and in all age subgroups. However, the location of coronary stenoses did not show important differences between men and women with the left anterior descending being the most frequently involved artery. Furthermore, the calculated Gensini index, which reflects cumulatively the extent, severity and location of coronary stenoses, was significantly higher in men (59.2 +/- 34.6 vs 52.2 +/- 36.2, p = 0.03), implying more severe and extensive CAD.(ABSTRACT TRUNCATED AT 250 WORDS) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect