Hand, Foot, and Mouth Syndrome in an Immunocompetent Adult: a Case Report

Autor: Manuel Vaz Riscado, João Carlos Silva, Bárbara Flor de Lima, Nuno Riso, Ana Grilo, Ana Rodrigues
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Adult
Male
Abdominal pain
medicine.medical_specialty
Pathology
Myocarditis
Myocarditis/immunology
HCC INF
Hand
Foot and Mouth Disease/pathology

Case Report
Disease
Myocarditis/complications
Acute Pharyngitis
General Biochemistry
Genetics and Molecular Biology

Coxsackie A9
Hand
Foot and Mouth Disease/complications

medicine
Celiac Disease/pathology
Humans
Celiac Disease/virology
Hand
Foot and Mouth Disease/immunology

Myopericarditis
Myocarditis/virology
Enterovirus B
Human/isolation & purification

Medicine(all)
Hand
Foot and Mouth Disease/virology

Hand
foot
and mouth syndrome

Biochemistry
Genetics and Molecular Biology(all)

business.industry
General Medicine
Enterovirus B
Human/immunology

medicine.disease
Dermatology
Enterovirus B
Human

Myocarditis/pathology
Celiac Disease
Acute Disease
Celiac Disease/immunology
medicine.symptom
Immunocompetence
Hand
Foot and Mouth Disease

business
Odynophagia
Foot (unit)
Celiac Disease/complications
Zdroj: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
BMC Research Notes
Popis: BACKGROUND: Hand, foot, and mouth syndrome (HFMS) is a common acute illness. It is characterized by mild clinical symptoms including fever, blisters, and sores in the mouth and on the palms and soles following a 3- to 7-day incubation period. This syndrome is rarely seen in adults. CASE PRESENTATION: A 35-year-old male Caucasian patient had a history of multiple episodes of acute pharyngitis, hypertension, hypercholesterolemia, and occasional abdominal pain. He presented with polyarthralgia in the knees and hands and odynophagia, followed by fever, oral mucosal aphthous lesions, and vesicles on the palms and soles. Three weeks after presentation, he was admitted to the emergency room with acute myocarditis. The in-hospital evaluation revealed positive serology for coxsackie A9 (1:160), positive anti-transglutaminase and anti-gliadin antibodies, normal immunoglobulins, and human immunodeficiency virus negativity. CONCLUSION: We herein describe a case of HFMS that was associated with coxsackie A9 infection complicated by acute myocarditis. Although an association between celiac disease and HFMS has not been described, this patient's immunologic disruption could have favored the development of infection and ultimately HFMS.
Databáze: OpenAIRE