HIV and hepatitis C treatment uptake among people who use drugs participating in the Amsterdam Cohort Studies, 1985–2015

Autor: Jannie J. van der Helm, Karen Lindenburg, Maarten F. Schim van der Loeff, Maria Prins, Daniela K van Santen
Přispěvatelé: AII - Infectious diseases, APH - Global Health, Graduate School, Other departments, Infectious diseases, Amsterdam institute for Infection and Immunity
Rok vydání: 2017
Předmět:
Zdroj: International journal on drug policy, 47, 95-101. Elsevier
ISSN: 0955-3959
1873-4758
DOI: 10.1016/j.drugpo.2017.05.026
Popis: Background: HIV-positive people who use drugs (PWUD) start antiretroviral therapy (ART) later than other risk groups, and among HCV-positive PWUD, HCV treatment uptake is low. Nowadays, HCV direct acting antivirals (DAAs) are available and reimbursed in the Netherlands (since 2014). The Amsterdam Cohort Studies (ACS), initiated in 1985, provides us the opportunity to describe temporal trends in ART and HCV-treatment uptake among PWUD through 2015. Methods: We analyzed data from PWUD participating in the ACS between 1985 and 2015. ART and HCV-treatment data were obtained from ACS questionnaires and medical records. Treatment uptake was defined by: treatment initiation (the proportion initiating any kind of ART/HCV treatment when treatment-naive) and coverage (the proportion ever treated for HIV/HCV) among all HIV-/HCV-RNA-positive PWUD. Each was calculated per calendar year. We estimated the cumulative probability of ART uptake in the pre-cART (
Databáze: OpenAIRE