An international collaborative study of 105 new cases of adenomatoid odontogenic tumors
| Autor: | Oslei Paes de Almeida, Roman Carlos, Willie F. P. van Heerden, Ana Luiza Oliveira Corrêa Roza, Alan Roger Santos-Silva, Pablo Agustin Vargas, Mário José Romañach, Márcio Ajudarte Lopes, Bruno Augusto Benevenuto de Andrade, Adalberto Mosqueda-Taylor |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Anterior maxilla Odontogenic Tumors Mandible Pathology and Forensic Medicine Ameloblastoma Young Adult 03 medical and health sciences 0302 clinical medicine Oral and maxillofacial pathology medicine Humans Radiology Nuclear Medicine and imaging Dentistry (miscellaneous) Back Posterior mandible Adenomatoid odontogenic tumor business.industry 030206 dentistry medicine.disease Dermatology Odontogenic Multicenter study 030220 oncology & carcinogenesis Female Surgery Oral Surgery business Posterior maxilla Brazil |
| Zdroj: | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 132:327-338 |
| ISSN: | 2212-4403 |
| Popis: | Objective The aim of this study was to report the clinicopathologic features of 105 new cases of adenomatoid odontogenic tumor (AOT) from Brazil, Guatemala, Mexico, and South Africa. Study Design Clinical and radiographic data were collected from records of 5 oral pathology laboratories, and all cases were microscopically reviewed. Results This series of cases included 36 (34.2%) from South Africa; 33 (31.4%) from Brazil; 23 (21.9%) from Mexico; and 13 (12.3%) from Guatemala. Seventy-two patients (68.5%) were females and 33 patients (31.4%) were males, with an average age of 19.2 years. The tumors predominantly affected the anterior maxilla (48.5%), followed by the anterior mandible (29.5%); posterior mandible (15.2%); and posterior maxilla (6.6%). Sixty-three tumors (63.6%) were follicular, 34 (34.3%) were extrafollicular, and 2 (2%) were peripheral. In most cases, the tumors caused considerable cortical expansion (average size 3.4 cm). Microscopically, most cases showed rosette-like and duct-like structures. Conclusions This is one of the largest case series of AOTs reported in the literature and the first multicenter study involving populations from Latin America and South Africa. In a fifth of the present cases, the posterior regions of the gnathic bones were affected and the tumors demonstrated larger sizes compared with cases occurring in other populations. |
| Databáze: | OpenAIRE |
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