High convection volume in online post-dilution haemodiafiltration : relevance, safety and costs
| Autor: | Ira M. Mostovaya, Muriel P.C. Grooteman, Peter J. Blankestijn, Christoph Wanner, Camiel L.M. de Roij van Zuijdewijn, Andrew Davenport, Carlo Basile, Menso J. Nubé |
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| Přispěvatelé: | Nephrology, ICaR - Circulation and metabolism, ACS - Diabetes & metabolism |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
safety
medicine.medical_specialty medicine.medical_treatment costs Bioinformatics convection volume Post-dilution law.invention Randomized controlled trial law medicine Journal Article In patient ddc:610 Intensive care medicine Cardiovascular mortality hemodiafiltration Transplantation integumentary system business.industry medicine.disease mortality Haemodialysis Nephrology Contents Observational study Narrative review Hemodialysis business Kidney disease |
| Zdroj: | Clinical Kidney Journal, 8(4), 368. Oxford University Press Clinical kidney journal, 8(4), 368-373. Oxford University Press Mostovaya, I M, Grooteman, M P C, Basile, C, Davenport, A, de Roij van Zuijdewijn, C L M, Wanner, C, Nube, M J & Blankestijn, P J 2015, ' High convection volume in online post-dilution haemodiafiltration: relevance, safety and costs ', Clinical kidney journal, vol. 8, no. 4, pp. 368-373 . https://doi.org/10.1093/ckj/sfv040 Clinical kidney journal, 8(4), 368-73. Oxford University Press Clinical Kidney Journal |
| ISSN: | 2048-8505 |
| DOI: | 10.1093/ckj/sfv040 |
| Popis: | Increasing evidence suggests that treatment with online post-dilution haemodiafiltration (HDF) improves clinical outcome in patients with end-stage kidney disease, if compared with haemodialysis (HD). Although the primary analyses of three large randomized controlled trials (RCTs) showed inconclusive results, post hoc analyses of these and previous observational studies comparing online post-dilution HDF with HD showed that the risk of overall and cardiovascular mortality is lowest in patients who are treated with high-volume HDF. As such, the magnitude of the convection volume seems crucial and can be considered as the 'dose' of HDF. In this narrative review, the relevance of high convection volume in online post-dilution HDF is discussed. In addition, we briefly touch upon some safety and cost issues. |
| Databáze: | OpenAIRE |
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