Is the Freedom SOLO Stentless Bioprosthesis a Useful Tool for Patients with Aortic Endocarditis and Aortic Annular Destruction?
| Autor: | Herko Grubitzsch, Lorenzo Di Bacco, Laszlo Gazdag, Giuseppe Santarpino, Alberto Repossini, Claudio Muneretto, Alessandra Stara, Theodor Fischlein |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male Reoperation medicine.medical_specialty Time Factors medicine.medical_treatment stentless bioprostheses 030204 cardiovascular system & hematology Prosthesis Design Prosthesis 03 medical and health sciences 0302 clinical medicine Postoperative Complications Aortic valve replacement Recurrence Risk Factors Germany medicine Endocarditis Humans In patient Cardiac skeleton aortic valve endocarditis aortic annulus abscess Abscess Aged Retrospective Studies Bioprosthesis Heart Valve Prosthesis Implantation business.industry EuroSCORE Recovery of Function Middle Aged medicine.disease Confidence interval Progression-Free Survival Surgery Europe 030228 respiratory system Aortic Valve Heart Valve Prosthesis Female Cardiology and Cardiovascular Medicine business |
| Popis: | Background The Freedom SOLO (FS) stentless bovine-pericardial prosthesis with a supra-annular implantation technique can be a viable option for patients with endocarditic annular destruction. We assessed early- and long-term outcomes following the use of this prosthesis in extensive aortic valve endocarditis. Methods From 2006 to 2016, 59 patients with extensive aortic endocarditis underwent aortic valve replacement (AVR) with FS (cumulative follow-up 263 patients-years) in three European centers; all patients presented annular tissue infection, while 54.3% of patients had annular abscess. Results Mean age was 66 ± 11 years and mean EuroSCORE I was 30.3% (standard deviation: 24.1%). In our series, 30.5% of patients had prosthetic valve endocarditis. Early mortality was 15.2% (nine patients). Estimated overall survival at 5 and 10 years was 68.9% (95% confidence interval [CI]: 62.8–75.0%) and 59.1% (95% CI: 66.8–81.2%), respectively. At 10-year survival, freedom from valve-related death was 83.7% (95% CI: 80.9–86.5%). No structural valve deterioration was reported in this series. Five patients (8.5%) had recurrent endocarditis during follow-up and two of them underwent reoperation. Survival freedom from reoperation and endocarditis at 10-year follow-up was 88.0% (CI: 80.4–95.6%) and 86.7% (CI: 80.5–92.9%), respectively. Conclusion FS stentless bioprosthesis is a valuable and simple option to achieve AVR in patients with extensive aortic annulus endocarditis. Although in this group of complex patients, early mortality remains considerably high, late survival outcomes are comparable to the more technically demanding homografts and conventional stentless bioprostheses, with low rates of endocarditis recurrence. |
| Databáze: | OpenAIRE |
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