Developing limits for driving under cannabis

Autor:	Gero Leson, Bud Perrine, Johannes G. Ramaekers, Herbert Moskowitz, Gunter Berghaus, Rob Tunbridge, Marie Longo, Hans-Peter Krüger, Alison M. Smiley, Olaf H. Drummer, Franjo Grotenhermen
Přispěvatelé:	Neuropsychology & Psychopharmacology, RS: FPN NPPP II
Jazyk:	angličtina
Rok vydání:	2007
Předmět:	Drug Automobile Driving Marijuana Abuse media_common.quotation_subject Medicine (miscellaneous) Poison control Hashish Risk-Taking Risk Factors Environmental health mental disorders Injury prevention medicine Humans Cannabis media_common Psychomotor function biology business.industry Accidents Traffic biology.organism_classification Substance Abuse Detection Psychiatry and Mental health Drug Monitoring Psychomotor Disorders Risk assessment Psychomotor disorder business medicine.drug
Zdroj:	Addiction, 102 (12), 1910-7. Wiley
ISSN:	1360-0443 0965-2140
DOI:	10.1111/j.1360-0443.2007.02009.x
Popis:	Objective Development of a rational and enforceable basis for controlling the impact of cannabis use on traffic safety. Methods An international working group of experts on issues related to drug use and traffic safety evaluated evidence from experimental and epidemiological research and discussed potential approaches to developing per se limits for cannabis. Results In analogy to alcohol, finite (non-zero) per se limits for delta-9-tetrahydrocannabinol (THC) in blood appear to be the most effective approach to separating drivers who are impaired by cannabis use from those who are no longer under the influence. Limited epidemiological studies indicate that serum concentrations of THC below 10 ng/ml are not associated with an elevated accident risk. A comparison of meta-analyses of experimental studies on the impairment of driving-relevant skills by alcohol or cannabis suggests that a THC concentration in the serum of 7-10 ng/ml is correlated with an impairment comparable to that caused by a blood alcohol concentration (BAC) of 0.05%. Thus, a suitable numerical limit for THC in serum may fall in that range. Conclusions This analysis offers an empirical basis for a per se limit for THC that allows identification of drivers impaired by cannabis. The limited epidemiological data render this limit preliminary.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e2d1533822d6b3dc8a9973701d050f https://doi.org/10.1111/j.1360-0443.2007.02009.x Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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