Effectiveness of rapid SARS-CoV-2 genome sequencing in supporting infection control for hospital-onset COVID-19 infection: Multicentre, prospective study

Autor:	Stirrup, Oliver, Blackstone, James, Mapp, Fiona, MacNeil, Alyson, Panca, Monica, Holmes, Alison, Machin, Nicholas, Shin, Gee Yen, Mahungu, Tabitha, Saeed, Kordo, Saluja, Tranprit, Taha, Yusri, Mahida, Nikunj, Pope, Cassie, Chawla, Anu, Cutino-Moguel, Maria-Teresa, Tamuri, Asif, Williams, Rachel, Darby, Alistair, Robertson, David L, Flaviani, Flavia, Nastouli, Eleni, Robson, Samuel, Smith, Darren, Loose, Matthew, Laing, Kenneth, Monahan, Irene, Kele, Beatrix, Haldenby, Sam, George, Ryan, Bashton, Matthew, Witney, Adam A, Byott, Matthew, Coll, Francesc, Chapman, Michael, Peacock, Sharon J, COG-UK HOCI Investigators, COVID-19 Genomics UK (COG-UK) Consortium, Hughes, Joseph, Nebbia, Gaia, Partridge, David G, Parker, Matthew, Price, James Richard, Peters, Christine, Roy, Sunando, Snell, Luke B, De Silva, Thushan I, Thomson, Emma, Flowers, Paul, Copas, Andrew, Breuer, Judith
Přispěvatelé:	Stirrup, Oliver [0000-0002-8705-3281], Blackstone, James [0000-0003-4335-5269], MacNeil, Alyson [0000-0001-8409-2755], Robertson, David L [0000-0001-6338-0221], Flaviani, Flavia [0000-0002-4210-0451], Peacock, Sharon J [0000-0002-1718-2782], Partridge, David G [0000-0002-0417-2016], Breuer, Judith [0000-0001-8246-0534], Apollo - University of Cambridge Repository
Rok vydání:	2022
Předmět:	viral genomics Infection Control Cross Infection hospital-acquired infection SARS-CoV-2 infectious disease microbiology COVID-19 global health infection prevention molecular epidemiology Hospitals healthcare-associated infection Humans epidemiology human Prospective Studies
DOI:	10.17863/cam.89941
Popis:	Peer reviewed: True Funder: Medical Research Council; FundRef: http://dx.doi.org/10.13039/501100000265 BACKGROUND: Viral sequencing of SARS-CoV-2 has been used for outbreak investigation, but there is limited evidence supporting routine use for infection prevention and control (IPC) within hospital settings. METHODS: We conducted a prospective non-randomised trial of sequencing at 14 acute UK hospital trusts. Sites each had a 4-week baseline data collection period, followed by intervention periods comprising 8 weeks of 'rapid' (
Databáze:	OpenAIRE
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