Impact of Chronic Kidney Disease on the Presentation and Outcome of Patients Hospitalized With Atrial Fibrillation: Insights From Qatar
| Autor: | Imtiaz Salim, Jassim Al Suwaidi, Awad Al-Qahtani, Rajvir Singh, Hajar A. AlBinali, Nidal Asaad, Amar M Salam |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Population 030232 urology & nephrology Disease 030204 cardiovascular system & hematology Chest pain 03 medical and health sciences 0302 clinical medicine Internal medicine Atrial Fibrillation Odds Ratio medicine Humans Hospital Mortality Registries Renal Insufficiency Chronic education Qatar Stroke Aged Retrospective Studies education.field_of_study business.industry Anticoagulants Atrial fibrillation Retrospective cohort study Odds ratio Middle Aged medicine.disease Hospitalization Female medicine.symptom Cardiology and Cardiovascular Medicine business Anti-Arrhythmia Agents Kidney disease |
| Zdroj: | Angiology. 69:212-219 |
| ISSN: | 1940-1574 0003-3197 |
| DOI: | 10.1177/0003319717717849 |
| Popis: | Atrial fibrillation (AF) with coexistent chronic kidney disease (CKD) is poorly described in the literature. We compared the presenting symptoms, clinical characteristics, treatment, and outcome of patients hospitalized with AF with and without CKD in a large clinical registry. Data of patients hospitalized with AF between 1991 and 2012 in Qatar were analyzed. Of 5201 patients hospitalized for AF, 264 (5.1%) had CKD. Patients with AF and CKD were older with higher prevalence of other comorbidities and left ventricular dysfunction and were more likely to present with shortness of breath and chest pain compared with patients with AF alone who were more likely to present with palpitation. The crude in-hospital mortality was 3 times higher in patients with dual disease. On multivariable adjustments, CKD was an independent predictor of mortality (odds ratio: 2.84; 95% confidence interval: 1.33-6.08, P = .001). Further studies are warranted to try to reduce the increased mortality observed in this high-risk population. |
| Databáze: | OpenAIRE |
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