Controlled-release oxycodone compared with controlled-release morphine in the treatment of cancer pain: a randomized, double-blind, parallel-group study

Autor:	Sharon M. Weinstein, Peter T. Silberstein, Robert Francis Kaiko, Robert F. Reder, Linda R. Bressler, Marc L. Citron, Patricia Mucci-LoRusso, Barry S. Berman, Barbara J. Buckley
Rok vydání:	1997
Předmět:	Creatinine business.industry law.invention chemistry.chemical_compound Anesthesiology and Pain Medicine chemistry Opioid Randomized controlled trial law Anesthesia Morphine Medicine Itching medicine.symptom business Cancer pain Oxycodone medicine.drug Oxycodone/naloxone
Zdroj:	European journal of pain (London, England). 2(3)
ISSN:	1090-3801
Popis:	Controlled-release oral formulations of oxycodone and morphine are both suitable analgesics for moderate to severe pain. They were compared in cancer-pain patients randomized to double-blind treatment with controlled-release oxycodone (n = 48) or controlled-release morphine (n = 52) every 12 h for up to 12 days. Stable analgesia was achieved by 83% of controlled-release oxycodone and 81% of controlled-release morphine patients in 2 days (median). Following titration to stable analgesia, pain intensity (0=none to 3=severe) decreased from baseline within each group (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d4018e67ce157e4074c9eb8e6f1bcf https://pubmed.ncbi.nlm.nih.gov/15102384 Zobrazit plný text záznamu Plný text