Choriocapillaris Island: an optical coherence tomography angiography finding observed in central serous chorioretinopathy
| Autor: | Teresa K Gerges, Rania G. Estawro, Alaa E Fayed, Dina Baddar |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty animal structures genetic structures Demographics Focal area Central serous chorioretinopathy Imaging modalities Neovascularization 03 medical and health sciences 0302 clinical medicine lcsh:Ophthalmology Ophthalmology medicine Fundus fluorescein angiography Retinal pigment epithelium business.industry Choriocapillaris Optical coherence tomography angiography eye diseases Serous fluid 030104 developmental biology medicine.anatomical_structure lcsh:RE1-994 030221 ophthalmology & optometry Original Article sense organs medicine.symptom business psychological phenomena and processes |
| Zdroj: | International Journal of Retina and Vitreous, Vol 7, Iss 1, Pp 1-8 (2021) International Journal of Retina and Vitreous |
| ISSN: | 2056-9920 |
| Popis: | Purpose To report the observation of the choriocapillaris island (CCI) on optical coherence tomography angiography (OCTA) in eyes with active central serous chorioretinopathy (CSCR), and to investigate its associated clinical features. Design Retrospective observational study. Methods Patients diagnosed with active CSCR underwent OCTA imaging (Optovue Inc, Fremont, California, USA), and the software built-in en face choriocapillaris slab was examined to demonstrate CCI, defined as an area of detectable choriocapillaris flow surrounded by an area of undetectable or diminished flow. Electronic medical records (EMR) were reviewed for demographics, clinical data, other imaging modalities and any intervention, and these parameters were correlated with CCI findings. Results 25 eyes of 25 patients were recruited. CCI was detected in all examined eyes and was best elucidated on the en face choriocapillaris density maps. 24 eyes had focal retinal pigment epithelium (RPE) alterations overlying CCI. All 14 eyes with simultaneous fundus fluorescein angiography (FA) showed actively leaking point(s) well corresponding to the CCI location. Resolution of sub-retinal fluid in 4 eyes was associated with disappearance of CCI on follow-up OCTA scans. 1 eye showed complicating neovascularization 5 months after the initial presentation at the same location of the CCI. Conclusion We demonstrate the observation of the “choriocapillaris island” an OCTA finding in eyes with active CSCR underneath the area of neurosensory detachment. CCI may constitute an angiographic representation of the focal area of choriocapillaris structural and functional affection, with secondary RPE alteration jeopardizing its barrier function. Larger longitudinal studies are needed to further elucidate this finding. |
| Databáze: | OpenAIRE |
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