Relationship between herpesviruses and periodontal disease progression
| Autor: | Robert J. Danaher, Pinar Emecen-Huja, Dolphus R. Dawson, Richard J. Kryscio, Jeffrey L. Ebersole, Craig S. Miller, Chunmei Wang |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Herpesvirus 4 Human Congenital cytomegalovirus infection Cytomegalovirus Disease Virus Article 03 medical and health sciences 0302 clinical medicine medicine Humans 030212 general & internal medicine Periodontitis Epstein–Barr virus infection Herpesviridae biology business.industry 030206 dentistry medicine.disease biology.organism_classification Real-time polymerase chain reaction Immunology Disease Progression Periodontics Anaerobic bacteria business Bacteria |
| Zdroj: | J Clin Periodontol |
| ISSN: | 1600-051X |
| Popis: | AIM To investigate the role of Epstein-Barr virus (EBV), cytomegalovirus (CMV), and anaerobic bacteria in the progression of periodontitis. METHODS Eighty-one adults with generalized moderate to severe periodontitis were randomly assigned to: oral hygiene or scaling and root planning ± placebo or polyunsaturated fatty acids fish oil. Subgingival plaque samples collected from three healthy and three disease sites at weeks 0, 16, and 28 and from sites demonstrating disease progression were analysed for EBV, CMV, P. gingivalis (Pg), T. forsythia (Tf), and T. denticola (Td) DNA using quantitative polymerase chain reaction. RESULTS Cytomegalovirus was detected in 0.3% (4/1454) sites. EBV was present in 12.2% of healthy sites (89/728) and 27.6% disease sites (201/726; p |
| Databáze: | OpenAIRE |
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