Guidelines for Clinical Target Volume Definition for Perineural Spread of Major Salivary Gland Cancers
| Autor: | A. Blayney, R. Kileen, N.M. Hughes, Alina Mihai, John Armstrong, K. Armstrong, J. Ward, C. Mascott |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Standard of care Postoperative radiotherapy Planning target volume Perineural invasion Computed tomography 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Major Salivary Gland medicine Humans Neoplasm Invasiveness Radiology Nuclear Medicine and imaging Peripheral Nerves medicine.diagnostic_test business.industry Soft tissue Prognosis Salivary Gland Neoplasms Oncology 030220 oncology & carcinogenesis Practice Guidelines as Topic Perineural spread Radiology Neoplasm Recurrence Local Tomography X-Ray Computed business |
| Zdroj: | Clinical Oncology. 30:773-779 |
| ISSN: | 0936-6555 |
| DOI: | 10.1016/j.clon.2018.08.018 |
| Popis: | Aims Postoperative radiotherapy is the standard of care for resected major salivary cancers that are at risk of locoregional recurrence. Of the various histological subtypes, perineural invasion is most common in adenoidcystic carcinomas of the three major salivary glands – parotid, submandibular and sublingual. The clinical target volume (CTV) for these cases must include the relevant cranial nerve pathways at risk. A contouring atlas was devised for delineation of the CTV of the nerves supplying the major salivary glands. Materials and methods Using standard anatomy texts and e-anatomy sources the nerves supplying the major salivary glands were identified. Subsequently the pathways of the nerves were drawn on an archived patient's planning computed tomography scan. Results The innervation of the major salivary glands has been identified and studied. Both bone and soft tissue CTVs have been delineated. A full set of images and CTVs of all the relevant transverse computed tomography slices has been archived, a number of which are printed in this article. Conclusions Variation in CTV delineation is a recognised problem in a variety of anatomic sites. Guidelines and atlases can standardise practice and may improve the safety and efficacy of therapy. An atlas has been generated to guide clinicians in delineating the CTVs for perineural spread in major salivary gland cancers. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect