Management of Cerebral Microbleeds in Clinical Practice
Autor: | Naveed Akhtar, Saadat Kamran, Ashfaq Shuaib, Richard Camicioli |
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Rok vydání: | 2018 |
Předmět: |
0301 basic medicine
medicine.medical_specialty Neurology medicine.medical_treatment Brain Ischemia 03 medical and health sciences 0302 clinical medicine Internal medicine Medicine Dementia Humans Contraindication Stroke Cerebral Hemorrhage business.industry Cerebral infarction General Neuroscience Anticoagulants Brain Thrombolysis Vascular surgery medicine.disease 030104 developmental biology Cardiology Neurology (clinical) Neurosurgery Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery |
Zdroj: | Translational stroke research. 10(5) |
ISSN: | 1868-601X |
Popis: | Cerebral microbleeds (CMBs) are very frequent diagnoses with MRI imaging in the elderly or in patients with cerebral infarction, intracranial hemorrhage (ICH), and dementia. The mechanisms for CMBs are not fully understood but may be secondary to injury to the vascular wall from long-standing hypertension or amyloid deposition in the tissue. The presence of CMB increases the risk for stroke, dementia, and death. The increasing number of CMBs is also associated with a higher risk of hemorrhagic complications with the long-term use of anticoagulants in atrial fibrillation and in patients requiring thrombolysis for acute stroke. The presence of CMBs is however not a contraindication for anticoagulation or thrombolysis as was recently shown from the results of the CROMIS-2 study. This review will summarize our current understanding of the natural history of CMBs and offer suggestions on the best management in common clinical settings. |
Databáze: | OpenAIRE |
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