Adenovirus vectors for gene expression
| Autor: | Robert J. Natuk, Satoshi Mizutani, Bruce B. Mason, Paul P. Hung, Michael D. Lubeck, Alan R. Davis, Bernard J. Selling, Murty Chengalvala, Ramesh A. Bhat, Pranab K. Chanda, Bheem M. Bhat, Kuo-Hom Lee Hsu |
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| Rok vydání: | 1991 |
| Předmět: |
Genetics
Vaccines Synthetic Genetic Vectors Biomedical Engineering Human immunodeficiency virus (HIV) Gene Expression Heterologous Bioengineering Genetic Therapy HSL and HSV Biology medicine.disease_cause Virology Adenoviridae Gene expression medicine Animals Humans Cloning Molecular High level expression Gene Biotechnology |
| Zdroj: | Current Opinion in Biotechnology. 2:718-722 |
| ISSN: | 0958-1669 |
| DOI: | 10.1016/0958-1669(91)90041-3 |
| Popis: | Adenoviruses possess a combination of features that make them highly suitable as vectors for expression of heterologous genes. Non-conditional and non-defective adeno-vectors have been constructed to obtain high level expression of a number of foreign genes and some of them have been shown in animal models to exhibit excellent promise as vaccine candidates. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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