Being Treated In Higher Volume Hospitals Leads To Longer Progression-Free Survival For Epithelial Ovarian Carcinoma Patients in the Rhone-Alpes region of France

Autor: Jocelyne Provencal, Pierre Meeus, Fadila Farsi, Pierre De Saint Hilaire, Dominique Beal Ardisson, Lionel Perrier, Magali Morelle, Philippe Gabelle, Olivia Bally, Céline Chauleur, David Benayoun, Isabelle Ray-Coquard, Xavier Joutard, Nathalie Havet, Marius Huguet, Amandine Charreton, Olivier Glehen
Přispěvatelé: Groupe d'analyse et de théorie économique (GATE Lyon Saint-Étienne), École normale supérieure - Lyon (ENS Lyon)-Université Lumière - Lyon 2 (UL2)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS), Centre Léon Bérard [Lyon], Department of Radiation Oncology, Centre Hospitalier Universitaire Lyon Sud, Pierre Benite, France, Hospices Civils de Lyon (HCL), Hôpital privé Jean Mermoz, Laboratoire de Sciences Actuarielle et Financière (SAF), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, Laboratoire d'économie et de sociologie du travail (LEST), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Service d'Oncologie Chirurgicale, Université Grenoble Alpes - UFR Médecine (UGA UFRM), Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Groupe de recherche sur la thrombose (GRT (EA 3065)), Université Jean Monnet [Saint-Étienne] (UJM), Ciblage thérapeutique en Oncologie (EA3738), Réseau Espace Santé Cancer, Rhône-Alpes, Service d'Oncologie Médicale, Centre National de la Recherche Scientifique (CNRS)-Université de Lyon-Université Jean Monnet [Saint-Étienne] (UJM)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université Lumière - Lyon 2 (UL2)-École normale supérieure - Lyon (ENS Lyon), Groupe d'Analyse et de Théorie Economique Lyon - Saint-Etienne (GATE Lyon Saint-Étienne), École normale supérieure de Lyon (ENS de Lyon)-Université Lumière - Lyon 2 (UL2)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Economie et de Sociologie du Travail (LEST), Groupe de recherche sur la thrombose, pharmacologie des antithrombotiques et situations à risque (GRT), Université Jean Monnet - Saint-Étienne (UJM)
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Disease management program
medicine.medical_specialty
Multivariate analysis
Databases
Factual
Propensity score
endocrine system diseases
media_common.quotation_subject
education
Carcinoma
Ovarian Epithelial
Disease-Free Survival
Health administration
03 medical and health sciences
0302 clinical medicine
Internal medicine
Humans
Medicine
Neoplasms
Glandular and Epithelial
030212 general & internal medicine
Progression-free survival
health care economics and organizations
Aged
Retrospective Studies
media_common
Ovarian Neoplasms
Selection bias
Proportional hazards model
business.industry
lcsh:Public aspects of medicine
Health Policy
lcsh:RA1-1270
Retrospective cohort study
Middle Aged
Epithelial ovarian cancer
[SHS.ECO]Humanities and Social Sciences/Economics and Finance
Hospitals
female genital diseases and pregnancy complications
3. Good health
Treatment Outcome
030220 oncology & carcinogenesis
Cohort
Propensity score matching
Centralization of care
Female
France
business
Research Article
Zdroj: BMC Health Services Research
BMC Health Services Research, BioMed Central, 2018, 18 (3), 11 p. ⟨10.1186/s12913-017-2802-2⟩
BMC Health Services Research, Vol 18, Iss 1, Pp 1-11 (2018)
BMC Health Services Research, 2018, 18 (3), 11 p. ⟨10.1186/s12913-017-2802-2⟩
ISSN: 1472-6963
DOI: 10.1186/s12913-017-2802-2⟩
Popis: Background To investigate the relationship between hospital volume activities and the survival for Epithelial Ovarian Carcinoma (EOC) patients in France. Methods This retrospective study using prospectively implemented databases was conducted on an exhaustive cohort of 267 patients undergoing first-line therapy during 2012 in the Rhone-Alpes Region of France. We compared Progression-Free Survival for Epithelial Ovarian Carcinoma patients receiving first-line therapy in high- (i.e. ≥ 12 cases/year) vs. low-volume hospitals. To control for selection bias, multivariate analysis and propensity scores were used. An adjusted Kaplan-Meier estimator and a univariate Cox model weighted by the propensity score were applied. Results Patients treated in the low-volume hospitals had a probability of relapse (including death) that was almost two times (i.e. 1.94) higher than for patients treated in the high-volume hospitals (p
Databáze: OpenAIRE
Externí odkaz: