Partner Bereavement and Detection of Dementia: A UK-Based Cohort Study Using Routine Health Data
| Autor: | Krishnan Bhaskaran, Liam Smeeth, Sigrún Alba Jóhannesdóttir Schmidt, Harriet Forbes, Marcus Richards, Angel Y S Wong, Caroline E Morton, Charlotte Warren-Gash, Sinead Langan |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Male diagnosis Health Status Health data Cohort Studies 0302 clinical medicine Risk Factors Epidemiology RISK Aged 80 and over education.field_of_study General Neuroscience Hazard ratio General Medicine Middle Aged 3. Good health PREVALENCE Psychiatry and Mental health Clinical Psychology Clinical Practice Research Datalink epidemiology Female Cohort study Research Article Adult medicine.medical_specialty Population VALIDATION 03 medical and health sciences medicine Dementia Humans Dementia diagnosis Psychiatry education METAANALYSIS Aged Proportional hazards model business.industry medicine.disease COGNITIVE FUNCTION United Kingdom 030104 developmental biology Geriatrics and Gerontology business 030217 neurology & neurosurgery dementia Bereavement |
| Zdroj: | Journal of Alzheimer's Disease Forbes, H J, Wong, A Y S, Morton, C, Bhaskaran, K, Smeeth, L, Richards, M, Schmidt, S A J, Langan, S M & Warren-Gash, C 2019, ' Partner Bereavement and Detection of Dementia : A UK-Based Cohort Study Using Routine Health Data ', Journal of Alzheimer's Disease, vol. 72, no. 2, pp. 653-662 . https://doi.org/10.3233/JAD-190571 |
| ISSN: | 1875-8908 1387-2877 |
| Popis: | Background: In the UK, an estimated one third of people with dementia have not received a diagnosis. Good evidence suggests that dementia risk is increased among widowed individuals; however, it is not clear if they are being diagnosed in routine primary care.Objective: This study aimed to investigate if bereavement influenced the probability of having received a dementia diagnosis.Methods: A population-based cohort study using UK electronic health records, between 1997 and 2017, among 247,586 opposite-sex partners. Those experiencing partner bereavement were matched (age, sex, and date of bereavement) to a non-bereaved person living in a partnership. Multivariate cox regression was performed.Results: Partner bereavement was associated with an increased risk of receiving a diagnosis of dementia in the first three months (hazard ratio (HR) 1.43, 95%CI 1.20-1.71) and first six months (HR 1.24, 95%CI 1.09-1.41), while there was a small reduced risk of getting a dementia diagnosis over all follow-up (HR 0.94, 95%CI 0.89-0.98).Conclusions: Partner bereavement appears to lead to a short-term increased risk of the surviving partner receiving a diagnosis of dementia, suggesting that bereavement unmasks existing undiagnosed dementia. Over the longer term, however, bereaved individuals are less likely to have a diagnosis of dementia in their health records than non-bereaved individuals. |
| Databáze: | OpenAIRE |
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