Prevalence of cocaine and derivatives in blood and urine samples of trauma patients and correlation with injury severity: a prospective observational study
| Autor: | Karina Diniz Oliveira, Eduardo Mello De Capitani, Rafael Lanaro, André Moreno Morcillo, Fábio Bucaretchi, Gustavo Pereira Fraga, José Luiz Costa, R C S de Azevedo, Emilio Ce Baracat, V C Gimenes, A I Ferreira Filho |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Multivariate analysis Adolescent Urine Critical Care and Intensive Care Medicine Logistic regression 03 medical and health sciences 0302 clinical medicine Cocaine Risk Factors Humans Medicine Orthopedics and Sports Medicine Longitudinal Studies Prospective Studies Risk factor Aged Aged 80 and over 030222 orthopedics Trauma Severity Indices business.industry 030208 emergency & critical care medicine Odds ratio Middle Aged Revised Trauma Score Substance Abuse Detection Cross-Sectional Studies Anesthesia Emergency Medicine Wounds and Injuries Injury Severity Score Female Surgery Observational study business Brazil |
| Zdroj: | European Journal of Trauma and Emergency Surgery. 45:159-165 |
| ISSN: | 1863-9941 1863-9933 |
| Popis: | The abuse of cocaine and its derivatives presents a likely risk factor for injury. Trauma incurred by cocaine and derivative abusers may be more severe than that incurred by non-users.To ascertain the presence of cocaine and its derivatives in trauma patients and to correlate RTS (Revised Trauma Score) and ISS (Injury Severity Score) with the presence of cocaine and its derivatives in blood and urine samples.All trauma victims treated in an emergency unit between November 11, 2012 and September 15, 2013 were included in the study. Blood and urine samples were collected on admission to hospital. RTS and ISS scores were then compared with the presence or absence of cocaine and its derivatives in the samples. The associations between RTS 7.84 and ISS 16 and the independent variables were evaluated by the gross odds ratio values, determined by univariate logistic regression. Multivariate analysis was performed using multivariate logistic regression.Of 453 patients (83.7% male) included in the study, 28.6% presented ISS 16 and 33.6% presented RTS 7.84. A total of 435 samples were collected, and 86 (19.8%) provided positive samples for cocaine, 48 (11%) for crack and 69 (15.9%) for cocaethylene. Compared to other patients, drug users showed a greater probability of RTS 7.84 (2.18 times greater) and a greater probability of ISS 16 (1.76 times greater).For the trauma patients included in our study, the use of cocaine and its derivatives was shown to be associated with more severe traumas, as demonstrated by their RTS and ISS scores. |
| Databáze: | OpenAIRE |
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