Hemodynamic, ventilatory and gasometric evaluation of an experimental bronchopleural fistula
Autor: | Carolina Kosour, Marcos Mello Moreira, Maria Gabriela Cavicchia Toneloto, Antonio Luis Eiras Falcão, Luiz Cláudio Martins, Douglas Guimaraes de Oliveira, Gabriel Franco de Souza, Desanka Dragosavac, Joaquim Murray Bustorff-Silva |
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Jazyk: | angličtina |
Rok vydání: | 2015 |
Předmět: |
medicine.medical_specialty
Mean arterial pressure Cardiac output Time Factors RD1-811 Swine medicine.medical_treatment Bronchopleural fistula Hemodynamics law.invention Reference Values law medicine Animals Thoracotomy Cardiac Output Mechanical ventilation business.industry Reproducibility of Results Respiratory Tract Fistula Pleural Diseases medicine.disease Respiration Artificial Respiratory Function Tests Surgery Disease Models Animal Treatment Outcome Anesthesia Ventilation (architecture) Models Animal Drainage Bronchial Fistula Blood Gas Analysis Pulmonary Ventilation business |
Zdroj: | Acta Cirurgica Brasileira, Volume: 30, Issue: 1, Pages: 1-5, Published: JAN 2015 Acta Cirúrgica Brasileira v.30 n.1 2015 Acta Cirúrgica Brasileira Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) instacron:SBDPC Acta Cirurgica Brasileira, Vol 30, Iss 1, Pp 1-5 (2015) |
Popis: | PURPOSE:To investigate the hemodynamic and ventilatory changes associated with the creation of an experimental bronchopleural fistula (BPF) treated by mechanical ventilation and thoracic drainage with or without a water seal.METHODS :Six large white pigs weighing 25 kg each which, after general anesthesia, underwent endotracheal intubation (6mm), and mechanically ventilation. Through a left thoracotomy, a resection of the lingula was performed in order to create a BPF with an output exceeding 50% of the inspired volume. The chest cavity was closed and drained into the water sealed system for initial observation of the high output BPF.RESULTS:Significant reduction in BPF output and PaCO2 was related after insertion of a water-sealed thoracic drain, p< 0.05.CONCLUSION: Insertion of a water-sealed thoracic drain resulted in reduction in bronchopleural fistula output and better CO2 clearance without any drop in cardiac output or significant changes in mean arterial pressure. |
Databáze: | OpenAIRE |
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