A protocol to generate phthaloyl peroxide in flow for the hydroxylation of arenes

Autor:	Dionicio Siegel, Changxia Yuan, Anders M. Eliasen, Karin R. Claussen, Randal P. Thedford
Rok vydání:	2014
Předmět:	Hydroxylation chemistry.chemical_compound Phthaloyl peroxide chemistry Molecular Structure Organic Chemistry Phthalic Acids Organic chemistry Physical and Theoretical Chemistry Biochemistry Peroxide Peroxides
Zdroj:	Organic letters. 16(14)
ISSN:	1523-7052
Popis:	A flow protocol for the generation of phthaloyl peroxide has been developed. This process directly yields phthaloyl peroxide in high purity (>95%) and can be used to bypass the need to isolate and recrystallize phthaloyl peroxide, improving upon earlier batch procedures. The flow protocol for the formation of phthaloyl peroxide can be combined with arene hydroxylation reactions and provides a method for the consumption of peroxide as it is generated to minimize the accumulation of large quantities of peroxide.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b995ff19f821115638ba0bd7faebd4cb https://pubmed.ncbi.nlm.nih.gov/24988535 Zobrazit plný text záznamu