Successful Radical Pneumonectomy for a Primitive Neuroendodermal Tumor in the Lung: A Case Report and Review of the Literature
| Autor: | Jiankai Wang, Fanying Liu, Pan Yin, Hua Jiang, Duo Zhao, Peng Chen, Bingqing Yue, Jingyu Chen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
RD1-811 diagnosis medicine.medical_treatment CD99 Case Report Malignancy 03 medical and health sciences Pneumonectomy 0302 clinical medicine Ewing family of tumors Medicine primitive neuroendodermal tumors Lymph node pneumonectomy small round cell malignant tumors Lung business.industry 030224 pathology medicine.disease Dissection medicine.anatomical_structure 030220 oncology & carcinogenesis Surgery Sarcoma Radiology prognosis business |
| Zdroj: | Frontiers in Surgery, Vol 8 (2021) Frontiers in Surgery |
| DOI: | 10.3389/fsurg.2021.667467/full |
| Popis: | Peripheral primitive neuroendodermal tumors (PNETs) and Ewing's sarcoma belong to the Ewing family of tumors and are small round-cell malignancies originating from spinal cord cells. These tumors account for 5% of all small round-cell malignant neoplasms. PNETs that arise from the lung parenchyma without pleural or chest wall involvement are very rare. We report a case of an adult female with a large pulmonary PNET who had given birth just 1 month prior to the diagnosis. She had cough and expectoration for 6 months, and the preoperative examination showed no metastases. Thus, we performed radical pneumonectomy and lymph node dissection. The patient recovered well without surgical complications and was discharged 7 days after the surgery. Postoperative pathology confirmed that the tumor was a small round-cell malignancy, and the tumor cells were positive for CD99, Friend leukemia virus integration 1 (FLI-1), and neuron-specific enolase (NSE), which was consistent with the diagnosis of a PNET. For primary large pulmonary PNETs, radical pneumonectomy may be a safe surgical method, worthy of further application in clinical practice. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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