The Relationship between 25 (OH) D Levels (Vitamin D) and Bone Mineral Density (BMD) in a Saudi Population in a Community-Based Setting
| Autor: | Alia Gabr, Abdullah Alkhenizan, Suad Alsoghayer, Aneela Hussain, Abdelmoneim Eldali, Ahmed N. Mahmoud |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Male Cross-sectional study Osteoporosis Osteopenia and Osteoporosis Physiology Organic chemistry lcsh:Medicine Geographical locations 0302 clinical medicine Elderly Bone Density Prevalence Medicine and Health Sciences Community Health Services Vitamin D Connective Tissue Diseases lcsh:Science Community based Bone mineral education.field_of_study Multidisciplinary Vitamins Middle Aged Physical sciences Chemistry Nutritional deficiencies Connective Tissue Female Anatomy geographic locations Research Article Adult medicine.medical_specialty Asia Population education Saudi Arabia 030209 endocrinology & metabolism vitamin D deficiency 03 medical and health sciences Chemical compounds Rheumatology Internal medicine Organic compounds parasitic diseases medicine Vitamin D and neurology Humans Bone Aged Retrospective Studies Nutrition Vitamin D deficiency Biology and life sciences business.industry lcsh:R medicine.disease eye diseases Osteopenia 030104 developmental biology Endocrinology Cross-Sectional Studies Biological Tissue Age Groups Women's Health Population Groupings lcsh:Q People and places business |
| Zdroj: | PLoS ONE, Vol 12, Iss 1, p e0169122 (2017) PLoS ONE |
| ISSN: | 1932-6203 |
| Popis: | BACKGROUND Vitamin D deficiency has been linked to an increased risk of osteoporosis. Vitamin D deficiency has reached high levels in the Saudi population, but there is conflicting evidence both in the Saudi population, and worldwide, regarding the existence of a correlation between these low vitamin D levels and reduced BMD (bone mineral density), or osteoporosis. OBJECTIVE The objective of this study was primarily to determine whether there was a correlation between vitamin D deficiency and osteoporosis in the Saudi population. We aimed to investigate whether the high levels of vitamin D deficiency and insufficiency would translate to higher prevalence of osteoporosis, and whether there is a correlation between vitamin D levels and bone mineral density. MATERIALS AND METHODS This was a community based cross sectional study conducted in the Family Medicine Clinics at King Faisal Specialist Hospital and Research Centre in Riyadh, Saudi Arabia. Electronic records of 1723 patients were reviewed. Laboratory and radiology results were collected, including vitamin D levels, calcium levels, and bone mineral density scan results. RESULTS Among the whole population, 61.5% had moderate to severe vitamin D deficiency with levels less than 50nmol/L. 9.1% of the population had osteoporosis, and 38.6% had osteopenia. Among the whole population, there was no significant correlation between spine or total femoral BMD and serum 25(OH) D. CONCLUSION Vitamin D deficiency is prevalent in the Saudi population. However, no correlation has been found between vitamin D deficiency and reduced bone mineral density in any age group, in males or females, Saudis or Non-Saudis, in our population in Riyadh, Saudi Arabia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|