Diagnostic accuracy of imaging methods for the diagnosis of skeletal malignancies:A retrospective analysis against a pathology-proven reference
| Autor: | Mads Lausen Nielsen, Mine Benedicte Lange, Lars Jelstrup Petersen, Jeannette Demant Andersen, Hanna Järnum Lilholt, Mogens Vyberg |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Bone Neoplasms Diagnostic accuracy Sensitivity and Specificity Bone and Bones 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Fluorodeoxyglucose F18 medicine Medical imaging Retrospective analysis Humans Radiology Nuclear Medicine and imaging Radionuclide Imaging Computed tomography laser mammography Retrospective Studies medicine.diagnostic_test business.industry Reproducibility of Results Magnetic resonance imaging Retrospective cohort study General Medicine Magnetic Resonance Imaging Positron emission tomography Positron-Emission Tomography 030220 oncology & carcinogenesis Female Radiology Radiopharmaceuticals Tomography X-Ray Computed business Preclinical imaging |
| Zdroj: | Lange, M B, Nielsen, M L, Andersen, J D, Lilholt, H J, Vyberg, M & Petersen, L J 2016, ' Diagnostic accuracy of imaging methods for the diagnosis of skeletal malignancies : A retrospective analysis against a pathology-proven reference ', European Journal of Radiology, vol. 85, no. 1, pp. 61-67 . https://doi.org/10.1016/j.ejrad.2015.10.012 |
| DOI: | 10.1016/j.ejrad.2015.10.012 |
| Popis: | OBJECTIVES: To examine the diagnostic accuracy of imaging modalities in skeletal tumours versus pathology reports.MATERIALS AND METHODS: Pathology reports of bone biopsies were compared to diagnostic imaging with X-ray, computed tomography (CT), magnetic resonance imaging (MRI), bone scintigraphy (BS), and (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET/CT) performed within 6 months of biopsy.RESULTS: A total of 409 biopsies were included. Sensitivity and specificity were significantly different among the five modalities (pCONCLUSIONS: MRI and FDG-PET/CT showed comparable diagnostic characteristics in general, in individual tumour types, and in different bone lesions and locations. Nominally, they outperformed CT in most situations. The diagnostic accuracy of X-ray and BS were notably inferior to other modalities. |
| Databáze: | OpenAIRE |
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