Pediatric Sympathetic Ophthalmia: 20 Years of Data From a Tertiary Eye Center in India
| Autor: | Sudharshan Sridharan, Sudha K Ganesh, Saurabh Mistry, Vineeta Rao, Parthopratim Dutta Majumder, A.E. George, Jyotirmay Biswas |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Adolescent genetic structures Visual Acuity India Ocular hypertension Azathioprine Eye care Tertiary Care Centers Ophthalmology medicine Humans Child Strabismus Glucocorticoids Retrospective Studies Best corrected visual acuity business.industry Incidence Sympathetic ophthalmia Disease Management Effective management General Medicine Vitreoretinal surgery Prognosis medicine.disease eye diseases Child Preschool Pediatrics Perinatology and Child Health Ophthalmia Sympathetic Female business Immunosuppressive Agents medicine.drug |
| Zdroj: | Journal of Pediatric Ophthalmology & Strabismus. 57:154-158 |
| ISSN: | 1938-2405 0191-3913 |
| Popis: | Purpose: To examine the clinical profile of sympathetic ophthalmia among the pediatric age group. Methods: Retrospective review of patients 18 years and younger with sympathetic ophthalmia seen in a tertiary eye care center between 1997 and 2017. Results: Of 20 patients included in the study, 70% were male. The most common inciting event for sympathetic ophthalmia was trauma (85%), followed by vitreoretinal surgery (15%). All patients were treated with systemic steroids. Seventeen patients received additional corticosteroid-sparing immunosuppressive agents, and 4 patients (20%) required more than one immunosuppressive agent. Azathioprine was the most commonly used corticosteroid-sparing immunosuppressive agent. The most common complications were cataract (50%) and ocular hypertension (30%). The mean presenting best corrected visual acuity in the sympathizing eye was 1.15 ± 0.99 logarithm of the minimum angle of resolution (logMAR), which improved to 0.54 ± 1.00 logMAR following treatment. Visual outcome was good (6/12 or better) in 70% of the sympathizing eyes, and 3 of the exciting eyes in the current study had good visual outcomes after the treatment. Conclusions: Prompt and effective management with corticosteroid-sparing immunosuppressive therapy in children with sympathetic ophthalmia allows favorable control of the disease and retention of good visual acuity. [ J Pediatr Ophthalmol Strabismus . 2020;57(3):154–158.] |
| Databáze: | OpenAIRE |
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