Prognostic Significance of Tumor Doubling Time in Mass-Forming Type Cholangiocarcinoma
| Autor: | De Rose AM, Cucchetti A, Clemente G, Ardito F, Giovannini I, Ercolani G, Giuliante F, Pinna AD, Nuzzo, G |
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| Přispěvatelé: | De Rose AM, Cucchetti A, Clemente G, Ardito F, Giovannini I, Ercolani G, Giuliante F, Pinna AD, Nuzzo G |
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Multivariate analysis Settore MED/18 - CHIRURGIA GENERALE DOUBLING TIME Gastroenterology Cholangiocarcinoma Tumor doubling time Internal medicine HEPATIC SURGERY Humans Medicine Doubling time Pathological Survival rate Intrahepatic Cholangiocarcinoma Aged Intrahepatic cholangiocarcinoma Aged 80 and over Univariate analysis Liver resection business.industry HEPATOBILIARY DISEASES Patient survival Middle Aged Prognosis Tumor Burden Survival Rate Bile Ducts Intrahepatic Bile Duct Neoplasms Immunohistochemistry Female Surgery business ANALYSIS OF SURVIVAL |
| Zdroj: | Journal of gastrointestinal surgery 17 (2013): 739–747. doi:10.1007/s11605-012-2129-6 info:cnr-pdr/source/autori:De Rose AM, Cucchetti A, Clemente G, Ardito F, Giovannini I, Ercolani G, Giuliante F, Pinna AD, Nuzzo, G/titolo:Prognostic Significance of Tumor Doubling Time in Mass-Forming Type Cholangiocarcinoma/doi:10.1007%2Fs11605-012-2129-6/rivista:Journal of gastrointestinal surgery/anno:2013/pagina_da:739/pagina_a:747/intervallo_pagine:739–747/volume:17 |
| Popis: | OBJECTIVE: The aim of this study was to determine the prognostic significance of the preoperatively assessed tumor doubling time (DT) in patients undergoing liver resection for mass-forming intrahepatic cholangiocarcinoma (IHC). METHODS: We evaluated 79 patients who underwent curative resection for IHC, and in whom the same imaging technique was preoperatively available in two consecutive occasions, to allow the calculation of the DT. The influence of DT and other clinical and pathological variables on tumor recurrence and patient survival was determined by the Kaplan-Meier method and uni- and multivariate analysis. RESULTS: Median overall survival was 40 months; 1-, 3-, and 5-year survival rates were 86.1, 55.1, and 35.1 %, respectively. Median disease-free survival was 17 months; 1-, 3-, and 5-year disease-free survival rates were 62.0, 29.1, and 23.3 %, respectively. At univariate analysis, DT |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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