Detection and distribution of zoonotic pathogens in wild Norway rats (Rattus norvegicus) from Tehran, Iran
Autor: | Fatemeh Fallah, Mohammad Reza Pourmand, S Rafiei Tabatabaei, Taher Azimi, Leila Azimi, H. Peeri Dogaheh |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Bartonella
Veterinary medicine biology vector-borne pathogens Infectious and parasitic diseases RC109-216 Iran Coxiella burnetii biology.organism_classification bacterial infections and mycoses Microbiology Rattus norvegicus Streptobacillus moniliformis Serology urban environments zoonotic disease Infectious Diseases Rickettsia Leptospira TaqMan Leptospira spp bacteria Original Article Typing |
Zdroj: | New Microbes and New Infections, Vol 42, Iss, Pp 100908-(2021) New Microbes and New Infections |
ISSN: | 2052-2975 |
Popis: | This is the first study on the prevalence of vector-borne zoonotic pathogens found in Rattus norvegicus (R. norvegicus) in urban areas of Tehran, Iran. Serological tests were used to detect IgG antibodies against Coxiella burnetii (C. burnetii) and Rickettsia spp. using a commercial qualitative rat ELISA kit. The frequency of Streptobacillus moniliformis (S. moniliformis) and Bartonella spp. was determined using a conventional PCR method. Molecular detection and characterization of Leptospira spp. were conducted using TaqMan real-time PCR based on lipL32 gene and SecY typing methods. A total of 100 R. norvegicus rats were collected from five regions in Tehran, Iran, and investigated to determine their zoonotic pathogens. S. moniliformis and Bartonella spp. were detected in 23 of 100 (23%) and 17 of 100 (17%) R. norvegicus populations, respectively. The highest prevalence of S. moniliformis and Bartonella spp. with similar frequency rates (n = 6/20; 30%) was seen among the R. norvegicus rats captured from the northern and southern parts of Tehran, respectively. Seroreactivity against C. burnetii and Rickettsia spp. was detected in 4% and 1% of R. norvegicus, respectively. C. burnetii. was identified only in one rat captured from the eastern part of Tehran. Results showed that Leptospira spp. was detected only in two rats, collected from the southern part (n = 2/20; 10%) of Tehran. The secY typing method identified two different Leptospira species including L. interrogans and L. kirschneri. The results showed that urban rats might play an important role in transmission of zoonotic pathogens to humans. |
Databáze: | OpenAIRE |
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