Subacute sclerosing panencephalitis and brain stem involvement: a rare combination
| Autor: | Nandita Prabhat, Heena Kathuria, Ritu Shree, Rajveer Singh |
|---|---|
| Rok vydání: | 2023 |
| Předmět: |
Male
Myoclonus Pathology medicine.medical_specialty Cerebellum Adolescent Central nervous system Facial Paralysis Case Report Corpus callosum Subacute sclerosing panencephalitis Measles virus 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Basal ganglia Medicine Humans biology business.industry Electroencephalography General Medicine biology.organism_classification medicine.disease Magnetic Resonance Imaging Hyperintensity medicine.anatomical_structure Brainstem Subacute Sclerosing Panencephalitis business 030217 neurology & neurosurgery Brain Stem Measles |
| Zdroj: | BMJ Case Rep |
| ISSN: | 1757-790X |
| Popis: | Subacute sclerosing panencephalitis (SSPE) is a progressive lethal neurological inflammatory disease due to persistent, wild measles virus infection in the central nervous system that is seen most frequently in children and young adolescents. Atypical presentations are seen in up to 10% of cases. Most frequently and severely affected region in the brain is the parieto-occipital region of the brain. Less commonly involved organs are the cerebellum, basal ganglia and corpus callosum. Brainstem involvement is rare and usually occurs when other areas of brain are involved along with it. Here, we describe an unusual male patient of 15 years age, having SSPE with MRI of brain showing extensive involvement of brainstem with no significant involvement of other cortical structures of the brain. It is very rarely described in SSPE, but one should be vigilant about such involvement of brainstem and cerebellum, and SSPE should not be missed when brainstem hyperintensities are seen in MRI brain with or without other region of the brain to avoid misdiagnosis. |
| Databáze: | OpenAIRE |
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