Occupational exposure to low doses of ionizing radiation and cataract development: a systematic literature review and perspectives on future studies
| Autor: | Maria Blettner, Gaël P. Hammer, Kazuo Neriishi, Ulrike Scheidemann-Wesp, Henryk Wicke, Florence Samkange-Zeeb |
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| Rok vydání: | 2013 |
| Předmět: |
Pediatrics
medicine.medical_specialty Radiation business.industry Biophysics Radiation Dosage Cataract Ionizing radiation Systematic review Occupational Exposure Radiation Ionizing Epidemiology Humans Medicine Occupational exposure Radiation protection Risk factor Posterior subcapsular cataract Radiation Injuries business Nuclear medicine General Environmental Science Exposure assessment |
| Zdroj: | Radiation and Environmental Biophysics. 52:303-319 |
| ISSN: | 1432-2099 0301-634X |
| DOI: | 10.1007/s00411-013-0477-6 |
| Popis: | Ionizing radiation is a well-known but little understood risk factor for lens opacities. Until recently, cataract development was considered to be a deterministic effect occurring at lens doses exceeding a threshold of 5–8 Gy. Substantial uncertainty about the level and the existence of a threshold subsists. The International Commission on Radiation Protection recently revised it to 0.5 Gy. Based on a systematic literature review of epidemiological studies on exposure to low levels of ionizing radiation and the occurrence of lens opacities, a list of criteria for new epidemiological studies was compiled, and a list of potential study populations was reviewed. Among 24 publications finally identified, six report analyses of acute exposures in atomic bomb survivors and Chernobyl liquidators, and the others report analyses of protracted exposures in occupationally, medically or accidentally exposed populations. Three studies investigated a dose threshold: in atomic bomb survivors, the best estimates were 1 Sv (95 % CI |
| Databáze: | OpenAIRE |
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