IntralesionalCandidaAntigen Immunotherapy for the Treatment of Recalcitrant and Multiple Warts in Children
| Autor: | Fania Z. Muñoz Garza, Paula Aguilera Peirò, Mauricio Torres Pradilla, Eulàlia Baselga Torres M.D., Susana Baltà Cruz, María Eugenia Hernández Ruiz, Esther Roé Crespo |
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| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Antigens Fungal Adolescent medicine.medical_treatment Dermatology Injections Intralesional Risk Assessment Cohort Studies Sex Factors CANDIDA ANTIGEN Antigen Partial response Humans Medicine Child Complete response Candida Retrospective Studies business.industry Age Factors Retrospective cohort study Immunotherapy Complete resolution Surgery Treatment Outcome Child Preschool Pediatrics Perinatology and Child Health Female Patient Safety Warts business Large group Follow-Up Studies |
| Zdroj: | Pediatric Dermatology. 32:797-801 |
| ISSN: | 0736-8046 |
| Popis: | Background Intralesional injection of Candida antigen appears to be an effective alternative for the treatment of warts. Aim To determine the efficacy and safety of this treatment. Methods We retrospectively reviewed records of all children who received intralesional injection of Candida antigen at our center from January 2008 to July 2013. Results From a total of 220 patients, 156 (70.9%) had a complete response, 37 (16.8%) had a partial response, and 27 (12.2%) had no improvement. An average of 2.73 treatments was needed. Forty-seven of the patients with more than one wart (21.3%) also noted at least partial resolution of untreated warts at distant sites. Twenty-seven of the 47 patients (57.4%) had complete resolution. All treated patients experienced some discomfort at the time of the injection, but no serious side effects were reported. Discussion We report our results using this approach in a large group of children. Conclusion Intralesional injection of Candida antigen is an effective and safe therapy for children with multiple and recalcitrant cutaneous warts. |
| Databáze: | OpenAIRE |
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