Prognostic value of global left atrial peak strain in patients with acute ischemic stroke and no evidence of atrial fibrillation
Autor: | Gian Luigi Nicolosi, Elisabetta Rigamonti, Pietro Bassi, Andrea Sonaglioni, Massimo Baravelli, Michele Lombardo, Claudio Anzà, Elena Tagliabue, Antonio Vincenti |
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Rok vydání: | 2018 |
Předmět: |
Male
medicine.medical_specialty Speckle tracking echocardiography 030204 cardiovascular system & hematology Patient Readmission Brain Ischemia 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Risk Factors Left atrial Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Heart Atria Prospective Studies Prospective cohort study Stroke Acute ischemic stroke Cardiac imaging Aged Aged 80 and over business.industry Proportional hazards model Atrial fibrillation Middle Aged Prognosis medicine.disease Echocardiography Doppler Cardiology Atrial Function Left Female Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery |
Zdroj: | The International Journal of Cardiovascular Imaging. 35:603-613 |
ISSN: | 1573-0743 1569-5794 |
Popis: | Prognostic stratification of acute ischemic stroke (AIS) patients without atrial fibrillation (AF) remains a challenge. Two-dimensional speckle tracking echocardiography (2D-STE) has recently been introduced for dynamic evaluation of left atrial function. However only few data are actually available regarding the application of 2D-STE in AIS patients. The aim of our study was to assess the prognostic role of global left atrial peak strain (GLAPS), measured by 2D-STE, in AIS patients without AF history. Eighty-five AIS patients (mean age 74.1 ± 12.1 years, 49 males) with normal sinus rhythm on ECG and without AF history were enrolled in the prospective study. All patients underwent a complete echocardiographic study with 2D-STE. At 1 year follow-up, we evaluated the occurrence of a composite endpoint of all-cause mortality plus cardiovascular re-hospitalizations. GLAPS was markedly reduced in AIS patients (15.71 ± 4.70%), without any statistically significant difference between the stroke subtypes. At 1-year follow-up, 14 deaths and 17 hospital readmissions were detected in AIS subjects. On a multivariate Cox model, variables independently associated with the occurrence of the composite endpoint were the “Rankin in” Scale (HR 1.69, p = 0.001), GFR (HR 0.98, p = 0.03) and the GLAPS value (HR 0.78, p |
Databáze: | OpenAIRE |
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